I-123 MIBG Imaging of Metastatic Carcinoid Tumor From the Rectum

Watanabe, Naoto; Seto, Hikaru; Ishiki, Manabu; Shimizu, Masashi; Kageyama, Misao; Wu, Yiwei; Nagayoshi, T; Kamisaki, Yuichi; Kakishita, M

doi:10.1097/00003072-199504000-00014

Cited by 10 publications

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“…The use of somatostatin receptor scintigraphy is useful for identifying the presence of lymph node and distant metastases [ 20 ]. Iodine123-meta-iodobenzylguanidine (MIBG) may also be used [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

Management of sub-5 mm rectal carcinoids with lymph node metastases

Toh

Henderson

Yabe

et al. 2014

Gastroenterology Report

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Minute (<5 mm) and small (5–10 mm) rectal carcinoids discovered during colonoscopy are generally considered to be non-aggressive, and the management and surveillance of patients with this entity are usually limited. We present the case of a 61-year-old Chinese female with multiple sub-5 mm carcinoid tumours in the rectum without any computed tomography (CT) evidence of lymph node or distant metastases. She underwent an ultra-low anterior resection for a sessile rectal polyp with the histological appearance of a moderately differentiated adenocarcinoma. Seven foci of minute carcinoids in the rectum and perirectal lymph node metastastic spread from the carcinoid tumours were also discovered on histopathology. There were no lymph node metastases originating from adenocarcinoma. This case report and review of the literature suggests that minute rectal carcinoids are at risk of metastasizing and that these patients should be investigated for lymph node and distant metastatic spread with CT and somatostatin receptor scintigraphy or its equivalent, as this would influence prognosis and surgical management of these patients. Findings relating to lymphovascular invasion, perineural invasion, high Ki-67, mitotic rate, depth of tumour invasion, central ulceration, multifocal tumours and size are useful in predicting metastases and may be used in scoring tools. Size alone is not a good predictor of metastastic spread.

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Section: Discussionmentioning

confidence: 99%

Management of sub-5 mm rectal carcinoids with lymph node metastases

Toh

Henderson

Yabe

et al. 2014

Gastroenterology Report

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Carcinoid Tumors

Chevallier¹,

Baère²,

Padovani³

et al. 1999

Radiological Imaging of Endocrine Diseases

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Carcinoid disease

Neary¹,

Redmond²,

Houghton³

et al. 1997

Diseases of the Colon &Amp; Rectum

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Carcinoid syndrome is the product of a rare but fascinating malignant neoplasm. Carcinoid syndrome was described more than 100 years ago, and recent advances in diagnostic localization, elucidation of the mechanisms of oncogenesis, treatment options, and, consequently, patient prognosis have been made. Current modalities of treatment, possible therapeutic implications of new avenues of research, and current literature on the chemotherapeutic combinations used are reviewed.

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I-123 MIBG Imaging of Metastatic Carcinoid Tumor From the Rectum

Cited by 10 publications

References 0 publications

Management of sub-5 mm rectal carcinoids with lymph node metastases

Management of sub-5 mm rectal carcinoids with lymph node metastases

Carcinoid Tumors

Carcinoid disease

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