i(5)(p10) in acute myeloid leukemia

Isochromosome 5p-i(5)(p10)-represents a rare but recurrent abnormality in myeloid disorders, especially in acute myeloid leukemia. In all published cases, the isochromosome 5p was present in single copy and accompanied by one or more additional anomalies, mostly trisomy 8. Here we report a case of refractory cytopenia with multilineage dysplasia with two copies of isochromosome 5p, a single normal chromosome 5and an apparently balanced translocation between long arms of chromosome 7and 10. To our knowledge, the pentasomia 5p has never been described before the presentstudy.

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Two copies of isochromosome 5p in refractory cytopenia with multilineage dysplasia: A case report

Giudici

Lingeri

Patriarca

et al. 2013

Leukemia Research Reports

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i(5)(p10) in acute myeloid leukemia

Abstract: This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 France Licence.

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Two copies of isochromosome 5p in refractory cytopenia with multilineage dysplasia: A case report

Two copies of isochromosome 5p in refractory cytopenia with multilineage dysplasia: A case report

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