2022
DOI: 10.1515/chem-2022-0235
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Aconitum coreanum Rapaics: Botany, traditional uses, phytochemistry, pharmacology, and toxicology

Abstract: The present review summarizes the multifaceted uses and recent findings regarding the phytochemistry, traditional use, pharmacology, and toxicity of the extracts and compounds of Aconitum coreanum Rapaics (Ranunculaceae) for the first time to facilitate further research and exploitation of these types of compounds and the utilization of A. coreanum plants. A. coreanum is one of the most important medicinal Aconitum species and has been traditionally and popularly used in China and other Asian countries for the… Show more

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“…Studies have shown that the diterpenoid alkaloids from A. coreanum had anti-arrhythmic effects on cardiac sodium current [ 30 ], the total alkaloids from A. coreanum were correlation with atrial fibrillation [ 31 ], Guanfu base A and Guanfu base G had effect on HERG K + channel [ 32 ]. As a commonly used traditional Chinese medicine in clinical practice, A. coreanum also has a long history and good clinical efficacy in treating CIS [ 33 ]. However, there is a lack of research on the relationship between the components of A. coreanum and efficacy in treating CIS.…”
Section: Discussionmentioning
confidence: 99%
“…Studies have shown that the diterpenoid alkaloids from A. coreanum had anti-arrhythmic effects on cardiac sodium current [ 30 ], the total alkaloids from A. coreanum were correlation with atrial fibrillation [ 31 ], Guanfu base A and Guanfu base G had effect on HERG K + channel [ 32 ]. As a commonly used traditional Chinese medicine in clinical practice, A. coreanum also has a long history and good clinical efficacy in treating CIS [ 33 ]. However, there is a lack of research on the relationship between the components of A. coreanum and efficacy in treating CIS.…”
Section: Discussionmentioning
confidence: 99%