Artemisia pallensalleviates acetaminophen induced toxicity via modulation of endogenous biomarkers

Abstract

It is concluded that the methanol extract of Artemisia pallens alleviates APAP induced in rats toxicity through its antioxidative and anti-inflammatory actions.

Effects of Artemisia dracunculus Aqueous Extract on Blood Sugar, Serum Insulin, Triglyceride and Liver Enzymes in Fructose Drinking Water Male Rats

“…Our findings in the present study showed that consumption of Artemisia aqueous extract improved IRI in FDW + E group compared to FDW group and the results are in agreement with literature. Moreover, some tests have shown that diabetic and insulinresistant patients have higher blood glucose and hyperinsulinemia compared to normal population [18]. The liver is a main organ for the protection of lipid, glucose and hormonal homeostasis.…”

“…Extraction was obtained by mixing 20 grams of the powder in 200 mL of distilled water in a soxhelet apparatus for 24 hours. The prepared extract was filtered through a gauze cloth followed by filtration through a normal filter paper Watman no.1 [12,18]. The result was a brown aqueous extract which was dried subsequently in incubator for one day at 45º and sustained in refrigerator temperature (4°C).…”

“…Artemisia dracunculus aerial was separated, shade-dried in a room temperature and then changed into powder by hand [18]. Extraction was obtained by mixing 20 grams of the powder in 200 mL of distilled water in a soxhelet apparatus for 24 hours.…”

Antiulcer Potential of Morin in Acetic acid-Induced Gastric Ulcer via Modulation of Endogenous Biomarkers in Laboratory Animals

“…Elevated level of oxygen derived free radical is a hallmark of gastric ulceration which play pivotal role in disruption of gastro protective mechanism 28 . During the stressful conditions, SOD plays a vital role in maintenance of cellular oxidative balance 35,36 . It has a central role in detoxification of ROS via scavenging superoxide anion, that form hydrogen peroxide [37][38][39] .…”

In-vitro Free Radicals Scavenging and Antioxidant Activity of Rice Bran Extract

“…This eventuates in biological systems when there is an excessive synthesis of Reactive Oxygen Species (ROS) or Reactive Nitrogen Species (RNS) on one side at the same time an insufficiency of enzymatic and nonenzymatic antioxidants on the other [19][20][21][22][23][24][25][26][27][28] . This can be expressed in different way that, oxidative stress emerges from the metabolic processes that utilize oxygen and shows a disturbance in the equilibrium status of pro-oxidant or antioxidant reactions in living tissues.…”