<i>Aspergilli series Versicolores</i>: importance of species identification in the clinical setting

Géry, Antoine; Séguin, Virginie; Pécoulas, Philippe Eldin de; Bonhomme, Julie; Garon, David

doi:10.1080/1040841x.2022.2082267

Cited by 5 publications

(3 citation statements)

References 127 publications

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“…For instance, of the 60 phylogenetically distinct species of Aspergillus section Fumigati, approximately 20 were reported to cause infections both in humans and animals [50,51]. Aspergillus section Nidulantes series Versicolores has been proposed to contain 18 species, mainly cryptic, many of which are opportunistic pathogens [52]. Similar complexity is attributable to the sections Nigri and Flavi [53,54].…”

Section: Taxonomymentioning

confidence: 99%

What do We Know about Cryptic Aspergillosis?

Geremia,

Giovagnorio,

Colpani

et al. 2024

Microorganisms

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Cryptic Aspergillus species are increasingly recognized as pathogens involved in human disease. They are ubiquitarian fungi with high tenacity in their environment and can express various resistance mechanisms, often due to exposure to antifungal agents employed in agriculture and farming. The identification of such species is increasing thanks to molecular techniques, and a better description of this type of pathogen is granted. Nevertheless, the number of species and their importance in the clinical setting still need to be well studied. Furthermore, their cross-sectional involvement in animal disease, plants, and human activities requires a multidisciplinary approach involving experts from various fields. This comprehensive review aims to provide a sharp vision of the cryptic Aspergillus species, from the importance of correct identification to the better management of the infections caused by these pathogens. The review also accentuates the importance of the One Health approach for this kind of microorganism, given the interconnection between environmental exposure and aspergillosis, embracing transversely the multidisciplinary process for managing the cryptic Aspergillus species. The paper advocates the need for improving knowledge in this little-known species, given the burden of economic and health implications related to the diffusion of these bugs.

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Section: Taxonomymentioning

confidence: 99%

What do We Know about Cryptic Aspergillosis?

Geremia,

Giovagnorio,

Colpani

et al. 2024

Microorganisms

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“…These infections are generally associated with immunocompromised individuals, such as those with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) [ 10 ] or organ transplant recipients [ 11 ]. It is therefore important to identify the exact species involved in human pathologies in order to adapt treatment [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

“…In more recent years, further taxonomic revisions have been carried out using a combination of morphological, molecular, and chemical data and have revealed 17 species of Aspergillus series Versicolores [ 15 , 16 ]. In many studies, misidentifications have been observed between A. versicolor species and other species of Aspergillus series Versicolores [ 12 ]. As molecular and genomic tools continue to improve, a new revision of taxonomy was proposed in 2022 and was based on a combination of phylogenetic, morphological, and molecular features, including spore morphology, growth temperature, DNA sequence analysis, and osmotic tolerance.…”

Section: Introductionmentioning

confidence: 99%

Spectrometric Characterization of Clinical and Environmental Isolates of Aspergillus Series Versicolores

Jomat,

Géry,

Leudet

et al. 2023

JoF

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Aspergillus series Versicolores are molds distributed among 17 species, commonly found in our environment, and responsible for infections. Since 2022, a new taxonomy has grouped them into 4 major lineages: A. versicolor, A. subversicolor, A. sydowii, and A. creber. Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry (MALDI-TOF MS) could be a faster and more cost-effective alternative to molecular techniques for identifying them by developing a local database. To evaluate this technique, 30 isolates from Aspergillus series Versicolores were used. A total of 59 main spectra profiles (MSPs) were created in the local database. This protocol enabled accurate identification of 100% of the extracted isolates, of which 97% (29/30) were correctly identified with a log score ≥ 2.00. Some MSPs recorded as Aspergillus versicolor in the supplier’s database could lead to false identifications as they did not match with the correct lineages. Although the local database is still limited in the number and diversity of species of Aspergillus series Versicolores, it is sufficiently effective for correct lineage identification according to the latest taxonomic revision, and better than the MALDI-TOF MS supplier’s database. This technology could improve the speed and accuracy of routine fungal identification for these species.

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2023

Larone's Medically Important Fungi

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Aspergilli series Versicolores: importance of species identification in the clinical setting

Cited by 5 publications

References 127 publications

What do We Know about Cryptic Aspergillosis?

What do We Know about Cryptic Aspergillosis?

Spectrometric Characterization of Clinical and Environmental Isolates of Aspergillus Series Versicolores

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