2014
DOI: 10.1002/mame.201400276
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Bombyx moriSilk Fibers: An Outstanding Family of Materials

Abstract: Designing novel multifunctional materials from natural resources is a challenging goal that has increasingly attracted researchers. Recently, the great potential of silk fibers has been recognized. The target readers for this review are researchers from different backgrounds (i.e., non‐specialists in silk research) with special interests on the physical–chemical characterization of silk fibers, since their knowledge is crucial for the improvement of existent silk‐based biomaterials and the basis for the develo… Show more

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Cited by 100 publications
(105 citation statements)
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References 236 publications
(430 reference statements)
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“…Whereas silk II is characterized by an antiparallel β‐sheet structure, silk I occurs as a metastable state between a partial ordered α‐helix and the β‐sheet structures. Silk III is formed at air–liquid interfaces . The β‐sheet crystals of the silk II structure are the most stable protein secondary structures .…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Whereas silk II is characterized by an antiparallel β‐sheet structure, silk I occurs as a metastable state between a partial ordered α‐helix and the β‐sheet structures. Silk III is formed at air–liquid interfaces . The β‐sheet crystals of the silk II structure are the most stable protein secondary structures .…”
Section: Resultsmentioning
confidence: 99%
“…In recent years, the scientific community has recognized that silks can be a rich source of inspiration for the design of new materials with tailored properties, enhanced performance, and high added value for targeted applications, opening exciting new prospects in the domain of materials science and related technological fields, including biofriendly integration, miniaturization, and multifunctionalization . Extraordinary mechanical properties, self‐assembly, machinability, biocompatibility, and controllable biodegradability are some of the intrinsic characteristics of silk, transforming it into a quite outstanding material and overtaking other biopolymers and even some synthetic polymers.…”
Section: Introductionmentioning
confidence: 99%
“…Fibroin accounts for the major composition (>70% weight) of silkworm silk. Its primary structure can be approximately attributed to a composition of glycine (Gly), alanine (Ala), and serine (Ser) with a sequence of (-Gly-SerGly-Ala-Gly-Ala-) n , as illustrated in Figure 2 c. [ 61,76 ] Fibroin possesses a high molecular weight, consisting of repetitive crystalline hydrophobic heavy chains (ca. 390 kDa) and noncrystalline hydrophilic light chains (ca.…”
Section: Introductionmentioning
confidence: 99%
“…Sericin, constituting 25-30% of the weight of silk, is a water-soluble protein secreted by the caterpillar to glue the fi broin fi bers into a cocoon. [ 58,61 ] Sericin is often removed during the de-gumming process through boiling an alkaline solution and is subsequently discarded, as it causes immunity responses in humans. [ 51 ] After the removal of sericin, silkfi broin fi bers can be dissolved in aqueous solution with chaotropic agents.…”
Section: Introductionmentioning
confidence: 99%
“…INTRODUCTION Silk, a natural fiber produced by Bombyx mori silkworm, appears shiny and feels soft to the touch, and has been traditionally used as a high-end textile fiber for centuries. [1][2][3] Silk fibroin, the major component of silk, is endowed with a combination of impressive mechanical properties as well as good biocompatibility and biodegradability. [4][5][6] Furthermore, silk fibroin can be processed into different forms including sponges, hydrogels, films, and mats due to the versatile processability.…”
mentioning
confidence: 99%