2024
DOI: 10.1101/2024.03.12.584572
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Cdonis required for organ Left-Right patterning via regulating DFCs migration and the sequential ciliogenesis

Zhilin Deng,
Wenqi Chang,
Chengni Li
et al.

Abstract: Cdon and boc are members of the cell adhesion molecule subfamily III Ig/fibronectin. Although they were reported to be involved in muscle and neural development at late developmental stage, while their early roles in embryonic development are unknown. Here we discovered that zebrafish cdon but not boc was expressed in dorsal forerunner cells (DFCs) and epitheliums of Kupffer's vesicle (KV), implying the possible role of cdon in organ LR patterning. Further data showed that the liver and heart LR patterning was… Show more

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