Loss to follow-up contributes to the low coverage of HIV care interventions among HIV-exposed infants in Beira, Mozambique. This qualitative study explores the perceptions of HIV-infected women and their health care providers regarding the main obstacles preventing women from attending follow-up visits for HIV care, and factors influencing women's decisions about newborn care. Fifty-two in-depth interviews and two focus group discussions were conducted; transcripts were coded and analyzed using ATLAS.ti. Interviewees perceived three major barriers to follow-up: food insecurity, difficulties navigating the health system, and women's familial roles and responsibilities. Our findings unveil the complex context in which HIV-infected women and their children live, and suggest that the structure and function of the HIV care system should be reviewed. Economic empowerment of women is crucial to achieving better compliance with medical care. Integration of mother and child services and more efficient and culturally sensitive medical services may improve follow-up.
KeywordsHIV/AIDS, loss to follow-up, adherence, HIV care, access barriers 2 SAGE Open Maman, 2007;Manzi et al., 2005;Painter et al., 2005). Finally, structural factors, including the physical, social, cultural, organizational, community, economic, or policy aspects of the environment, can act as barriers or facilitators to individually oriented HIV prevention and care services (Blankenship, Bray, & Merson, 2000;Farmer, 2004;Farmer, Leandre, et al., 2001;Gupta, Parkhurst, Ogden, Aggleton, & Mahal, 2008;Jones et al., 2005;Parker, Easton, & Klein, 2000;Sumartojo, Doll, Holtgrave, Gayle, & Merson, 2000).However, few data have been systematically collected in Mozambique on the conditions that affect the lives of HIVpositive women and their children on a daily basis, and how these conditions affect their acceptance and utilization of HIV care services. We therefore conducted a qualitative study to determine the factors affecting women's decision to seek HIV care and adhere to follow-up visits for themselves and their newborn babies.
MethodWe conducted a cross-sectional qualitative study of a subset of women participating in an observational cohort study of nevirapine (NVP) resistance following prophylaxis with singledose nevirapine, which started in June 2005 and ended in December 2008 (Micek et al., 2010). Briefly, the study enrolled mothers and newborn infants participating in PMTCT programs at three clinics in Beira, Mozambique. Infants were supposed to make five study visits through 8 weeks of age, at which time questionnaires were administered and blood samples taken for analysis of HIV infection and NVP resistance (Blankenship et al., 2000). Similar to the PMTCT program from which participants were recruited, study-related followup of infants was poor, with 57% (499/875) of enrolled infants missing >2 successive scheduled study visits. We investigated the reasons for LTFU in this already assembled cohort of mothers and infants, to provide insights into...