<i>Chromolaena odorata</i>
            as a potential feed additive bioresource to alleviate heat stress in chickens in the humid tropics

Lartey, Kwame Ayisi; Kang, Dan-Ju; Zhang, Qiaohui; Shi, Chao-Qun; Yang, Fan; Lin, Heizhao; Gooneratne, Ravi; Chen, Jinjun

doi:10.1080/00439339.2020.1729673

Cited by 2 publications

(2 citation statements)

References 59 publications

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“…Which will mitigate lipid peroxidation and protect liver from damage. In another study, Chromolaena odorata was shown to contain polyphenols and antioxidant enzymes that activate biological defense mechanisms and stresssensing transcription factors to prevent oxidative damage and heat stress in chicken (Lartey et al, 2020). The study further indicated that Chromomoric acid C-1 from Chromolaena odorata methanol extract, at 10 µg, demonstrated antiinflammatory potential by activating Nrf2 and suppressing NF-κB at an inhibition capacity (IC50) of 6.9 µM.…”

Section: Antioxidant Property Of Chromolaena Odoratamentioning

confidence: 89%

Evaluation of the anti-oxidation and wound healing activities of Chromolaena odorata methanol leaf extract using rat model

Daniel Ikechukwu Oraekei,

Fortune Ebubechukwu Okonkwo,

Marcellus Ejike Nnamani

et al. 2023

World J. Bio. Pharm. Health Sci.

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Since decades ago, humans have been using natural products such as plants in medicines. Currently, traditional medicine has become popular. Plants contain numerous phytochemicals that may act synergistically through different mechanisms for prophylaxis and therapy of diseases. This study evaluated the anti-oxidative and wound healing activities of Chromolaena odorata methanol leaf extract using mature male rat models. Phytochemical analysis, acute toxicity study, anti-oxidative potentials as well as wound healing activities of the leaf extract were assessed. In anti-oxidative study, the effects of Chromolaena odorata methanol leaf extract on malondialdehyde (MDA) and catalase were tested. In the wound healing, excision wounds were created on the back of the rats and the wounds were treated with three different doses of Chromolaena odorata methanol leaf extract embedded in petroleum jelly. Cikatrin powder and petroleum jelly served as positive and negative controls respectively. The phytochemicals present were alkaloids, flavonoids, proteins, tannins, and steroids. LD50 ˃ 5,000 mg/kg body weight was noted. In anti-oxidative assay, the leaf extract had better lipid peroxidation inhibition. The 500 mg/kg body weight of the extract reduced MDA to 5.63 ± 0.33 x 10-5 µmol/ml compared to 14.16 ± 0.59 x 10-5 µmol/ml obtained with distilled water. The 5% and 10% extracts had better percentage wound healing of 95.52% and 97.14 % respectively than cikatrin which had 87.95% after 12 weeks of treatment. Chromolaena odorata methanol leaf extract had good safety profile and a dose dependent increase in wound healing that is significantly (p ˂ 0.05) more potent than cikatrin.

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Section: Antioxidant Property Of Chromolaena Odoratamentioning

confidence: 89%

Evaluation of the anti-oxidation and wound healing activities of Chromolaena odorata methanol leaf extract using rat model

Daniel Ikechukwu Oraekei,

Fortune Ebubechukwu Okonkwo,

Marcellus Ejike Nnamani

et al. 2023

World J. Bio. Pharm. Health Sci.

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“…Apart from being labeled as an evil weed (OISC, 2018) for its negative impacts on the agricultural systems (Ganguly et al, 2022), Siam weed (Chromolaena odorata) could serve as a potential alternative feed source for both ruminants and non-ruminants (Jiwuba et al, 2018;Tiamiyu & Okunlade, 2020) due to its high biomass production and high protein content (Oematan et al, 2020), and well-balanced amino acid profile (Fasuyi et al, 2005), and anti-oxidant properties (Lartey et al, 2020). However, its utilization as livestock feed remains challenging due to its inherent anti-nutrient properties (Olawale et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Improving the Rumen Molar Proportion of Glucogenic Volatile Fatty Acids with the Inclusion of Siam Weed (Chromolaena odorata) Meal in Pelleted Diet of Fattened Cattle

Mullik,

Dato,

Mulik

et al. 2024

Trop. Anim. Sci. J.

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The objective of this metabolism study was to evaluate the efficacy of Siam weed (Chromolaena odorata) meal in pelleted diets for fattened cattle. Four 2-year-old Bali steers were assigned to four dietary treatments using a 4x4 Latin square experimental design. The treatments were pellets containing chromolaena meal at 10% (10COM), 20% (20COM), 30% (30COM), or 40% (40COM). The pellet was given at 2% liveweight (LW), and kume (Sorghum plumosum var. Timorense) grass hay was offered ad libitum. The diets were isonitrogenous (20%) and energy (11.5 MJ ME/kg DM). Dietary intake, digestibility, and rumen fermentation were the variables measured. The results showed that increasing chromolaena meal to 40% substantially decreased the nutrient intake. Dry matter intake decreased from 2.5% LW in the 10COM to 2.19% LW in the 40COM. Likewise, crude protein intake decreased from 749 g/d (10COM) to 661 g/d (40COM). On the contrary, digestibility, rumen pH, ammonia concentration (116-125 mg/dL), and volatile fatty acids were not affected. It might be concluded that chromolaena can be used as a protein source for ruminants, but at high levels of inclusion (40%) tends to reduce intake.

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Chromolaena odorata as a potential feed additive bioresource to alleviate heat stress in chickens in the humid tropics

Cited by 2 publications

References 59 publications

Evaluation of the anti-oxidation and wound healing activities of Chromolaena odorata methanol leaf extract using rat model

Evaluation of the anti-oxidation and wound healing activities of Chromolaena odorata methanol leaf extract using rat model

Improving the Rumen Molar Proportion of Glucogenic Volatile Fatty Acids with the Inclusion of Siam Weed (Chromolaena odorata) Meal in Pelleted Diet of Fattened Cattle

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