<i>Dillenia</i>species: A review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies

Yazan, Latifah Saiful; Armania, Nurdin

doi:10.3109/13880209.2013.872672

Cited by 38 publications

(20 citation statements)

References 63 publications

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“…The plant possesses various medicinal properties like cancer, astringent, diarrhea, and laxative [16, 17]. It is used to treat fever and acts as a cooling agent to relieve body heat [18, 19]. It also possess several other activities like antimicrobial [20, 21], antioxidant [22, 23], analgesic [24], anti-inflammatory, and dysentery [17, 25].…”

Section: Dillenia Indica: Description and Its Traditional Usementioning

confidence: 99%

Therapeutic Benefit of Dillenia indica in Diabetes and Its Associated Complications

Kamboj

Talukdar

Banerjee

2019

Journal of Diabetes Research

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Diabetes, a metabolic disorder characterized by elevated fasting blood glucose levels, affects nearly 8% of the world population and was predicted that it would be the top seven leading cause of death in the next ten years. The incidence of diabetes and its morbidity are increasing rapidly in developing countries due to lifestyle change and intake of high-calorie diet occurring with urbanization. Medicinal plants and their products have been proven to be effective, less expensive, and safe for the treatment and prevention of diabetes. Although several medicinal plants known for the antidiabetic property are reported in the ancient medical textbook, there is always a scope to identify and validate less explored medicinal plants that are still practiced regularly by local and tribal people since ancient times. Here, in the present article, we would like to review a less explored medicinal plant, Dillenia indica, which has promising effects in treating diabetes and other diabetic-associated complications. In spite of its wide use in the Northeast region of India as traditional medicine, there is only one clinical study where the antidiabetic potential of the fruit powder has been shown. Further well-designed animal and human studies are needed to confirm the role of Dillenia indica in diabetes and its associated complications.

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Section: Dillenia Indica: Description and Its Traditional Usementioning

confidence: 99%

Therapeutic Benefit of Dillenia indica in Diabetes and Its Associated Complications

Kamboj

Talukdar

Banerjee

2019

Journal of Diabetes Research

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“…D. excelsa is edible fruit. This species has medical purposes and pharmacological properties [37]. Syzygium spp.…”

Section: Ex-situ Conservation By Collected Plantmentioning

confidence: 99%

Exploration of Flora Diversity and Recommending Species for Reclamation of Coal Mining with Biodiversity Concept in Besiq Bermai Forest, East Borneo

Trimanto

Shofiah

2018

J.Trop.Life.Science

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This research was conducted to gather basic information to support recovery coal mining area with study of flora biodiversity. Plants inventory were conducted explorative in Besiq Bermai forest. Some observations were conducted on plants as integral part of the documentation process. The result showed that there are 203 numbers of plant. They consist of 51 families of flora collection to be conserved in Purwodadi Botanic Garden. There are 53 species of orchid that collected from this forest, including of rare species and endemic orchid. There are 70 numbers of 1000 specimen floras to be collected in Nursery of coal mining to be used in reclamation program. There are 20 species of flora that be conserved because it is threatened species that based on IUCN. Ten species can be chosen to become pioneer species in reclamation of coal mining area. Biodiversity concept can be used in reclamation of post mining area. Prospective conservation area that called Arboretum is provided for in-situ conservation program. Some practical considerations are suggested for future reclamation projects.

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“…It is used by the rural people in the treatment of fever, constipation, dysentery, stomach ache, snake bite, burning sensation in the chest, food poisoning, bacterial infection, diabetes, etc. (Saiful and Armania, 2014). A growing body of evidence has revealed the potential of whole plant of D. indica as a source of various antioxidants, including polyphenols (Rahayu et al, 2020), flavonoids (Saha et al, 2009), triterpenoids and steroids (Kumar et al, 2011), etc. There is no complete data on total phenolic and flavonoid content, antioxidant capacity, radical scavenging activity and ferric reducing activity of extracts from D. indica bark.…”

Section: Introductionmentioning

confidence: 99%

In vitro Antioxidant and Free Radical Scavenging Activity of the Bark of Dillenia indica L.

et al. 2022

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The aim of the study was to explore the antioxidant and free radical scavenging activity of bark of Dillenia indica L. The methanolic extract (CME) of coarse powder of the dried bark was fractionated with pet-ether (PETF), chloroform (CHF), and water (AQF) and each fraction was investigated for antioxidant and free radical potentials. The phenolic contents of CME, CHF, PETF and AQF were found to be 90.2, 171.1, 52.1 and 158.1 and flavonoid contents 182.6, 340.2, 285.9, and 362.6 mg of GAE/g of dried extract, respectively. The total antioxidant activity of CME, PETF, CHF, AQF and standard catechin in terms of absorbance were 0.373, 0.707, 0.88, 1.051 and 0.804, respectively at 160 μg/ml concentration indicating AQF possessing the highest total antioxidant activity. In DPPH radical scavenging activity, the AQF and CHF showed potential radical scavenging activity followed by CME and PETF with IC50 values of 1.5, 2.5, 23 and 61 μg/ml, respectively, whereas standard ascorbic acid showed IC50 at 8 μg/ml. Among the extractives, AQF and CHF exhibited potent hydroxyl radical scavenging activity with IC50 values of 49.0 and 42 μg/ml followed by CME and PETF with IC50 of 86 and 168 μg/ml, respectively. In ferric-reducing antioxidant assay, AQF, CHF and CME (absorbance 2.262, 2.418 and 2.157, respectively) showed higher activity than that of standard (1.793) followed by PETF (absorbance 0.593). Since polyphenols like flavonoids play a vital role in controlling antioxidants, polyphenol rich extracts are potent source of antioxidants. Our data showed that the chloroform fraction of the bark of D. indica provided highest polyphenols and antioxidant activities, hence, can be used further as a source of natural antioxidants. Bangladesh Pharmaceutical Journal 25(1): 38-43, 2022 (January)

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Dilleniaspecies: A review of the traditional uses, active constituents and pharmacological properties from pre-clinical studies

Cited by 38 publications

References 63 publications

Therapeutic Benefit of Dillenia indica in Diabetes and Its Associated Complications

Therapeutic Benefit of Dillenia indica in Diabetes and Its Associated Complications

Exploration of Flora Diversity and Recommending Species for Reclamation of Coal Mining with Biodiversity Concept in Besiq Bermai Forest, East Borneo

In vitro Antioxidant and Free Radical Scavenging Activity of the Bark of Dillenia indica L.

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