(E)-1-(1,3-Benzodioxol-5-yl)-3-(2,4,5-trimethoxyphenyl)prop-2-en-1-one

Abstract

The molecule of the title compound C19H18O6, adopts anEconformation about the C=C double bond and the C—C=C—C torsion angle is −179.30 (16)°. The molecule is nearly planar, as indicated by the dihedral angle of 6.99 (6)° between the benzene ring and the benzodioxalane ring. In the crystal, molecules are linkedviaweak C—H...O hydrogen bonds, forming zigzag chains propagating along thebaxis.

Synthesis, Characterization and Antimicrobial Activities of Chalcones and Their Post Transformation to Pyrazole Derivatives

“…A collection of signal observed singlet for nine protons at δ 3.852 ppm and as multiplet for twelve protons in the region δ 7.218-7.965 ppm were assigned to OCH 3 and aromatic protons respectively. 13 C NMR and Mass spectra of the synthesized series of compounds 3b-g, which strongly supports the structure proof for the synthesized compounds.…”

“…All the compounds of the series 3a-g showed similar spectral and analytical data, among them the structure of 3g was confirmed by single crystal X-ray diffraction studies and was depicted in ORTEP diagram (Fig. 2) [13].…”

“…The spots were visualized under UV light. 1 H NMR and 13 C NMR spectra were recorded on Agilent-NMR 400 MHz and 100 MHz spectrometer respectively. The solvent CDCl3 with TMS as an internal standard was used to record the spectra.…”

“…The structural elucidation of the compounds, 3a-g were provided by 1 H NMR, 13 C NMR, Mass spectral studies and elemental analysis. The structural assignments were made by NMR analysis by considering compound, 5a as the representative compound among the series.…”

(E)-1-(Benzo[d][1,3]dioxol-5-yl)-3-(2,3-dichlorophenyl)prop-2-en-1-one

“…This value is comparable with the value of 6.99 (6) reported earlier between the aromatic rings in the related chalcone derivative (E)-1-(1,3-benzodioxol-5-yl)-3-(2,4,5-trimethoxy-phenyl)prop-2-en-1-one. (Sunitha et al, 2017). The trans conformation about the C7 C8 double bond in the central enone group is confirmed by the C4-C7 C8-C9 torsion angle, À172.9 (3) .…”