Exserohilum rostratum, a rare cause of opportunistic skin infection in children: Case report and review of the literature

Abstract

Exserohilum species are environmental molds that may rarely cause skin and nasal infections, especially in immunocompromised children. We present a 3-year-old girl with acute leukemia who presented with a skin infection caused by Exserohilum rostratum. Previously published cases of skin infections by Exserohilum spp. in children are reviewed.

Comparative mitochondrial genome analyses reveal conserved gene arrangement but massive expansion/contraction in two closely related Exserohilum pathogens

“…Recently, E. rostratum seemed to be better known as an opportunistic pathogen found in humans, causing keratitis, meningitis, subdermal fungal disease, etc. [15] , [16] , [17] . Between the above two closely related Exserohilum species with fairly different target hosts, comparative analysis was rarely performed.…”

Combination of debridation, vacuum system, and epidermal micrografting system for the treatment of an Exserohilum rostratum skin infection in a pediatric cancer patient

“…Immunosuppression is the main risk factor for developing this infection. [1][2][3][4] A 6-year-old male patient was diagnosed with common B-cell acute lymphoblastic leukemia (B-ALL), after attending the emergency room with malaise and prolonged fever over the last week, along with severe pancytopenia. He was admitted for further diagnostic studies and given appropriate therapy (protocol SEHOP-PETHEMA-2013 1 ).Chemotherapy consisted of prednisone, vincristine, daunorubicin, PEG-asparaginase, and triple intrathecal chemotherapy.…”