<i>Granulicatella adiacens</i>Bacteremia in an Elderly Trauma Patient

Gardenier, Jason C.; Hranjec, Tjasa; Sawyer, Robert G.; Bonatti, Hugo

doi:10.1089/sur.2010.059

Cited by 20 publications

(13 citation statements)

References 33 publications

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“…The lower prevalence and abundance of pathogenic genera suggest they are likely transient bacteria acquired from surrounding environment. Other bacterial species were commensal of human intestinal tract, such as, Granulicatella adiacens, Akkermansia muciniphila and anaerostipes hadrus that is found in human colon (Table 3) [31][32][33].…”

Section: Discussionmentioning

confidence: 99%

A glimpse of the bacteriome of Hyalomma dromedarii ticks infesting camels reveals human Helicobacter pylori pathogen

Elbir

Almathen

Alhumam

2019

J Infect Dev Ctries

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Introduction: The tick Hyalomma dromedarii is predominant in camels of Saudi Arabia and harbor multiple pathogens causing disease in humans and animals. Knowing the bacterial community of ticks is crucial for surveillance of known and newly emerging pathogens. Yet, the bacteriome of H. dromedarii remain unexplored to date. Methodology: In a cross-sectional survey, we used V3-V4 region of 16S rRNA to characterize the bacteriome of 62 whole H. dromedarii tick samples collected from camels found in Hofuf city in Saudi Arabia. Results: Sequencing results yielded 217 species incorporated into 114 genera, which in turn belong to the dominant phylum Proteobacteria (98%) followed by Firmicutes (1.38%), Actinobacteria (0.36%), Bacteroidetes (0.17%), meanwhile the phyla Cyanobacteria, Verrucomicrobia and unclassified bacteria were rarely detected. Francisella endosymbiont dominated the bacteriome of H. dromedarii ticks with average abundance of 94.37% and together with Salincoccus sp. accounted for 94.51% of the average sequences. The remaining bacteriome consisted of low abundance of potential pathogens and environmental bacteria. Of these pathogens, we found Helicobacter pylori in the tick H. dromedarii for the first time. Notably, Anaplasma, Ehrlichia and Rickettsia pathogens known to be found in H. dromedarii ticks were not detected. Conclusion: This first preliminary study advances our knowledge about the bacterial community of H. dromedarii ticks and provides a basis for pathogen surveillance and studying the influences of symbionts on vector competence. Presence of pathogens in ticks, raise concerns about potential transmission of these agents to humans or animals.

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Section: Discussionmentioning

confidence: 99%

A glimpse of the bacteriome of Hyalomma dromedarii ticks infesting camels reveals human Helicobacter pylori pathogen

Elbir

Almathen

Alhumam

2019

J Infect Dev Ctries

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“…OTU‐3 showed a 98% sequence identity to Granulicatella adiacens , a member of the family Carnobacteriaceae that is particularly abundant in the oral cavity and the gastrointestinal tract of humans. This bacterium has consistently been associated with invasive infections in humans and considered as an opportunistic pathogen carrying resistance to β‐lactams, tetracyclines, macrolides and fluoroquinolones (Cargill, Scott, Gascoyne‐Binzi, & Sandoe, ; Gardenier, Hranjec, Sawyer, & Bonatti, ; Shailaja, Sathiavathy, & Unni, ). OTU‐4 showed high sequence identity to Acinetobacter haemolyticus (98.5%).…”

Section: Discussionmentioning

confidence: 99%

“…This bacterium has consistently been associated with invasive infections in humans and considered as an opportunistic pathogen carrying resistance to b-lactams, tetracyclines, macrolides and fluoroquinolones (Cargill, Scott, Gascoyne-Binzi, & Sandoe, 2012;Gardenier, Hranjec, Sawyer, & Bonatti, 2011;Shailaja, Sathiavathy, & Unni, 2013). OTU-4 showed high sequence identity to Acinetobacter haemolyticus (98.5%).…”

Section: Effect Of Pollution On the Streambed Resistomementioning

confidence: 99%

Wastewater pollution differently affects the antibiotic resistance gene pool and biofilm bacterial communities across streambed compartments

et al. 2017

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Wastewater discharges introduce antibiotic residues and antibiotic-resistant bacteria (ARB) into surface waters. Both inputs directly affect the streambed resistome, either by exerting a selective pressure that favour the proliferation of resistant phenotypes or by enriching the resident communities with wastewater-associated ARB. Here, we investigated the impact of raw and treated urban wastewater discharges on epilithic (growing on rocks) and epipsammic (growing on sandy substrata) streambed biofilms. The effects were assessed by comparing control and impact sites (i) on the composition of bacterial communities; (ii) on the abundance of twelve antibiotic resistance genes (ARGs) encoding resistance to β-lactams, fluoroquinolones, sulphonamides, tetracyclines, macrolides and vancomycin, as well as the class 1 integron-integrase gene (intI1); (iii) on the occurrence of wastewater-associated bacteria, including putative pathogens, and their potential linkage to target ARGs. We measured more pronounced effects of raw sewage than treated wastewater at the three studied levels. This effect was especially noticeable in epilithic biofilms, which showed a higher contribution of wastewater-associated bacteria and ARB than in epipsammic biofilms. Comparison of correlation coefficients obtained between the relative abundance of both target ARGs and operational taxonomic units classified as either potential pathogens or nonpathogens yielded significant higher correlations between the former category and genes intI1, sul1, sul2 and ermB. Altogether, these results indicate that wastewater-associated micro-organisms, including potential pathogens, contribute to maintain the streambed resistome and that epilithic biofilms appear as sensitive biosensors of the effect of wastewater pollution in surface waters.

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“…It is a part of the normal flora of oral cavity, genitourinary and gastrointestinal tract rarely causing any disease. Reported infectious cases by G. adiacens include endocarditis and sepsis in immunocompromised patients and peritonitis, abscess, and severe infections in patients with prosthetic devices[ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Septic shock due to Granulicatella adiacens after endoscopic ultrasound-guided biopsy of a splenic mass: A case report

Cho¹,

Cho²,

Park³

et al. 2021

WJG

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BACKGROUND Endoscopic ultrasound-guided fine needle aspiration or biopsy (EUS-FNA or FNB) has become a popular method for diagnosing various lesions of the gastrointestinal tract and surrounding tissue due to the accuracy and safety. To the best of our knowledge, no case report of severe infection after EUS-FNB of a solid lesion in the spleen has been described. Herein, we report a rare case of septic shock after EUS-FNB of a splenic mass. CASE SUMMARY A 45-year-old male patient presented to the outpatient clinic due to an incidentally detected splenic mass. A definitive diagnosis could not be established based on the abdominal magnetic resonance imaging. EUS of the spleen showed a 6 cm-sized, relatively well-demarcated, heterogeneous mass, and EUS-FNB with a 22G needle was performed. Ten days after the procedure patient developed septic shock and a splenic abscess was identified. Blood culture revealed growth of Granulicatella adiacens . After the treatment with antibiotics the patient underwent surgical resection, and the pathological examination showed diffuse large B-cell lymphoma. The patient received chemotherapy and he is in complete remission. CONCLUSION Infection of a splenic mass after EUS-FNB is a rare complication and prophylactic antibiotics might be considered.

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Granulicatella adiacensBacteremia in an Elderly Trauma Patient

Cited by 20 publications

References 33 publications

A glimpse of the bacteriome of Hyalomma dromedarii ticks infesting camels reveals human Helicobacter pylori pathogen

A glimpse of the bacteriome of Hyalomma dromedarii ticks infesting camels reveals human Helicobacter pylori pathogen

Wastewater pollution differently affects the antibiotic resistance gene pool and biofilm bacterial communities across streambed compartments

Septic shock due to Granulicatella adiacens after endoscopic ultrasound-guided biopsy of a splenic mass: A case report

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