<i>Helicobacter pylori</i> in the tonsillar tissue: a possible association with chronic tonsillitis and laryngopharyngeal reflux

Šiupšinskienė, Nora; Katutiene, I; Jonikiene, V; Jančiauskas, Dainius; Vaitkus, Saulius

doi:10.1017/s0022215117000597

Cited by 37 publications

(42 citation statements)

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“…The presence of H. pylori showed a link with LPR, corroborating the data obtained in a meta‐analysis . A recent finding showed a positive relationship between H. pylori and LPR signs assessed by the Reflux Finding Score . The mode of transmission of this bacterium to the upper airway has been described .…”

Section: Discussionsupporting

confidence: 83%

Possible association between Helicobacter pylori infection and vocal fold leukoplakia

Chen

Yang

et al. 2018

Head & Neck

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Background Several studies have indicated the larynx as possible Helicobacter pylori (H. pylori) reservoirs. This study explored the association between H. pylori and vocal fold leukoplakia. Methods The case‐control study involved 51 patients with vocal fold leukoplakia and 35 control patients with vocal polyps. Helicobacter pylori was detected in tissues by the rapid urease test, nested polymerase chain reaction (PCR), and single‐step PCR. The H. pylori‐specific immunoglobulin antibodies were detected in plasma by enzyme‐linked immunosorbent assay (ELISA). Results Helicobacter pylori‐positive rate of vocal fold leukoplakia and vocal polyps was 23.5% versus 11.4% (P = .157), 37.2% versus 14.3% (P = .020), 27.5% versus 8.6% (P = .031), and 70.6% versus 68.6% (P = .841) detected by rapid urease test, nested PCR, single‐step PCR, and ELISA, respectively. Regression analysis indicated that H. pylori infection (P = .044) was the independent risk factor for vocal fold leukoplakia. Conclusion Helicobacter pylori infection exists in the larynx and may be associated with vocal fold leukoplakia.

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Section: Discussionsupporting

confidence: 83%

Possible association between Helicobacter pylori infection and vocal fold leukoplakia

Chen

Yang

et al. 2018

Head & Neck

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“…Rather surprisingly, chronic cough was significantly correlated with H. pylori infection even though the association was rather weak. The possible relationship between H. pylori infection and laryngopharyngeal reflux causing a chronic cough has been mentioned in the literature . The other explanation for the association may be throat and larynx irritation induced by the bacteria …”

Section: Discussionmentioning

confidence: 99%

Prevalence of Helicobacter pylori infection among junior high school students in Grudziadz, Poland

Szaflarska-Popławska

Soroczyńska-Wrzyszcz²

2018

Helicobacter

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Background The purpose of the study was to assess the prevalence of Helicobacter pylori infection among the junior high school students in city Grudziądz, Poland. Materials and methods A prospective cross‐sectional study among second junior high school students was conducted from September 2008 to June 2015 during seven consecutive school years. The studied group was 3241 students 13‐17 years old. The 13C‐urea breath test (UBT) was administered to all participants for current H. pylori infection. Clinical, sociodemographic, and hygienic risk factors for H. pylori positivity were analyzed in children with positive and negative UBT. Results Urea breath test was performed and results were obtained for 3067 of 3241 children, including 723 children (23.6%) with positive result (group 1) and 2344 children (76.4%) with negative result (group 2). The prevalence of H. pylori infection was not different in subsequent seven school years (P = 0.06) and depending on the gender (P = 0.57). In group 1 the cough and in group 2 the epigastric discomfort occurred more frequent (P = 0.04 and P = 0.002, respectively). In multivariate analysis, factors positively associated with prevalence of H. pylori were age >16 years (OR = 2.556; 95%CI 1.293‐5.025), living in old town district (OR = 1.374; 95%CI 1.097‐1.723), consumption of raw vegetables (OR 1.305; 95%CI 1.038‐1.642) or unboiled water (OR = 1.444; 95%CI 1.138‐1.832) and using collective catering facilities (OR 1.338; 95%CI 1.039‐1.724). Having a cat was protective against H. pylori (OR 0.78; 95%CI 0.614‐0.991). Conclusions Over the past 10 years, the prevalence of H. pylori infection in Polish adolescents has decreased. H. pylori infection remains problem closely associated with socioeconomic and sanitary conditions. Our results are important to develop prevention strategies for H. pylori‐related diseases.

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“…Similar findings were obtained in adults and children. Significant relationships between a positive H. pylori identification and laryngopharyngeal reflux‐related signs of vocal fold edema, diffuse laryngeal edema, and hypertrophy of the posterior commissure were revealed …”

Section: Helicobacter Pylori and Gastroesophageal Reflux Diseasementioning

confidence: 98%

Helicobacter pylori and nonmalignant upper gastrointestinal diseases

2018

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The review of the most important recent publications concerning the relation of Helicobacter pylori with peptic ulcer disease (PUD), noninvestigated and functional dyspepsia, and gastroesophageal reflux disease (GERD) is presented. H. pylori remains the main etiopathogenetic factor in complicated and uncomplicated PUD. Nevertheless, the role of nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin is increasing. The novel data did not confirm that PUD caused by NSAIDs and aspirin is less symptomatic. The role of glucocorticoids, immunosuppressants, and antidepressants seems to be of some importance. Although the involvement of H. pylori in functional dyspepsia is controversial, several data support the importance of H. pylori-induced gastritis in the pathogenesis of dyspeptic symptoms. Recent interventional studies have reported that H. pylori eradication improves dyspepsia mainly in areas with a high prevalence of this bacterium. Novel data regarding the relation of gastrointestinal peptides, ghrelin and obestatin, with H. pylori infection are also presented. Intriguing findings support the involvement of the gastric microbiota in the causation of chronic functional dyspepsia. Finally, some data concerning negative, positive, or neutral associations of H. pylori with gastroesophageal reflux disease (GERD) were published. In this context, today there is no evidence indicating that H. pylori eradication could worsen the symptoms or the course of GERD.

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Helicobacter pylori in the tonsillar tissue: a possible association with chronic tonsillitis and laryngopharyngeal reflux

Abstract: H pylori infection may be related to chronic tonsillitis and laryngopharyngeal reflux.

Cited by 37 publications

References 35 publications

Possible association between Helicobacter pylori infection and vocal fold leukoplakia

Possible association between Helicobacter pylori infection and vocal fold leukoplakia

Prevalence of Helicobacter pylori infection among junior high school students in Grudziadz, Poland

Helicobacter pylori and nonmalignant upper gastrointestinal diseases

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