<i>In situ</i> revascularisation for femoropopliteal graft infection: ten years of experience with silver grafts

Matić, Predrag; Tanasković, Slobodan; Babić, Srdjan; Gajin, Predrag; Jocić, Dario; Nenezić, Dragoslav; Ilijevski, Nenad; Vučurević, Goran; Radak, Djordje

doi:10.1177/1708538113504399

Cited by 12 publications

(3 citation statements)

References 14 publications

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“…232,233 In a study of 24 femoropopliteal bypasses replaced with silver impregnated PET grafts, the overall re-infection rate was 19%. 234 When rifampicin soaked grafts are used, the results of wound cultures (when available) should be considered, as data have shown that the micro-organism causing the infection was resistant or not susceptible to rifampicin in 31% of cases. 235 A biosynthetic collagen prosthesis (Omniflow II; LeMaitre, Burlington, MA, USA) has also been tested in the presence of graft infection.…”

mentioning

confidence: 99%

Editor's Choice – European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Vascular Graft and Endograft Infections

Chakfé

Diener

Lejay

et al. 2020

European Journal of Vascular and Endovascular Surgery

370

322

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DEDICATIONAfter studying medicine at Hanover Medical School and philosophy and social psychology at the Leibniz University Hanover, Omke E. Teebken joined the Christian Albrechts University in Kiel at the end of the 1990s as a research fellow at the Clinic for Cardiovascular Surgery headed by Professor Dr Axel Haverich, whom Omke E. Teebken later followed back to Hanover.In Hanover, besides working as a clinician, Omke E.Teebken was particularly active scientifically, contributing to the establishment of the then newly founded Leibniz Laboratories for Biotechnology and Artificial Organs (LEBAO). His work focused on regenerative medicine and tissue engineering, and subsequently he wrote his habilitation thesis in in this field. After basic training in cardiac surgery, he specialised clinically in vascular surgery and played a pioneering role in the development of this field. Before being appointed director of the Clinic for Vascular Surgery e Endovascular Surgery at the Peine Clinic in 2016, Omke E. Teebken headed the Vascular Surgery e Endovascular Surgery Division of the Department of Cardiothoracic, Thoracic, Transplantation and Vascular Surgery at Hanover Medical School. Professor Teebken was a highly appreciated, committed, and competent colleague and teacher.On 8 April 2019, Professor Teebken passed away after a short and severe illness. He was member and author of the ESVS guideline writing committee, an esteemed colleague, and friend.We will always honor his memory.

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mentioning

confidence: 99%

Editor's Choice – European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Vascular Graft and Endograft Infections

Chakfé

Diener

Lejay

et al. 2020

European Journal of Vascular and Endovascular Surgery

370

322

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“…There are no wide studies on these materials, and, therefore, no definitive conclusions can be drawn. There is still little evidence for silver-coated grafts and bovine-pericardium xenogenous grafts, and further studies are needed to confirm their efficacy in VGEIs [16,22,[129][130][131][132][133][134][135][136]. Autologous femoral veins may also be used for an in situ reconstruction of the aorto-iliac segment in VGEIs [137][138][139][140].…”

Section: Treatment Of Vgeimentioning

confidence: 99%

Infection of Vascular Prostheses: A Comprehensive Review

et al. 2023

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Vascular graft or endograft infection (VGEI) is a complex disease that complicates vascular-surgery and endovascular-surgery procedures and determines high morbidity and mortality. This review article provides the most updated general evidence on the pathogenesis, prevention, diagnosis, and treatment of VGEI. Several microorganisms are involved in VGEI development, but the most frequent one, responsible for over 75% of infections, is Staphylococcus aureus. Specific clinical, surgical, radiologic, and laboratory criteria are pivotal for the diagnosis of VGEI. Surgery and antimicrobial therapy are cornerstones in treatment for most patients with VGEI. For patients unfit for surgery, alternative treatment is available to improve the clinical course of VGEI.

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“…However, they are definitely not the final solution for this serious and possibly lethal outcome complication [ 9 ]. The rate of re-infections of silver coated grafts in the femoral-popliteal segment is reported to be 19% [ 10 ]. Continuity of infection and bacterial resistance was found in 31% of patients after replacement of infected vascular graft with rifampicin coated prostheses [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Collagen-Sealed Polyester Vascular Prostheses Functionalized by Polycatecholamine Coatings

Michalicha

Canal²,

Espona‐Noguera³

et al. 2022

IJMS

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Collagen-sealed polyester (PET) prostheses are commonly used in reconstructive vascular surgery due to their self-sealing properties. To prevent post-surgical infection, different modification methods have been tested but so far none have showed long-term satisfactory efficiency. For this reason, in the present study, a commercial collagen-sealed PET prosthesis was coated by a highly adhesive poly (L-DOPA) layer maintaining the sealing protein without losing the original properties and functionality. This modified (as proven by SEM, FTIR, XPS and contact angle) graft exhibited comparable wettability and elasticity as pristine commercial graft, as well as reduced hemolysis-inducing effect, lowered toxicity against human endothelial cells and reduced toxicity in Danio rerio model. Poly (L-DOPA)-coated grafts were shown to bind six times more aminoglycoside antibiotic (gentamicin) than pristine graft. Poly (L-DOPA)-coated antibiotic-bound prostheses exhibited an improved antibacterial activity (bacterial growth inhibition and anti-adhesive capacity) in comparison with pristine antibiotic-bound graft. Overall, poly (L-DOPA)-coatings deposited on PET vascular grafts can effectively functionalize collagen-sealed prostheses without the loss of protein sealing layer and allow for antibiotics incorporation to provide higher safety in biomedical applications.

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In situ revascularisation for femoropopliteal graft infection: ten years of experience with silver grafts

Abstract: Results of in situ implantation of silver-coated grafts for femoropopliteal prosthesis infection are according to our opinion acceptable, but the risk of reinfection remains.

Cited by 12 publications

References 14 publications

Editor's Choice – European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Vascular Graft and Endograft Infections

Editor's Choice – European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Vascular Graft and Endograft Infections

Infection of Vascular Prostheses: A Comprehensive Review

Collagen-Sealed Polyester Vascular Prostheses Functionalized by Polycatecholamine Coatings

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