<i>In Vitro</i> Activity of Twenty Commercially Available, Plant-Derived Essential Oils against Selected Dermatophyte Species

Nardoni, Simona; Giovanelli, Silvia; Pistelli, Luisa; Mugnaini, Linda; Profili, Greta; Pisseri, Francesca; Mancianti, Francesca

doi:10.1177/1934578x1501000840

Cited by 34 publications

(38 citation statements)

References 25 publications

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“…The observed in vivo efficacy of EO against dermatophytes has been confirmed with in vitro testing with veterinary isolates and studies testing compounds against veterinary isolates . When 20 EOs were assayed against clinical animal isolates of M. canis, T. mentagrophytes, T. erinacei, T. terrestre and M. gypseum , the three most effective EOs identified were Thymus serpyllum, Origanum vulgare and Litsea cubeba .…”

Section: Topical Antifungal Treatmentsmentioning

confidence: 74%

Diagnosis and treatment of dermatophytosis in dogs and cats.

Moriello

Coyner²,

Paterson

et al. 2017

Veterinary Dermatology

229

147

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Background -Dermatophytosis is a superficial fungal skin disease of cats and dogs. The most common pathogens of small animals belong to the genera Microsporum and Trichophyton. It is an important skin disease because it is contagious, infectious and can be transmitted to people.Objectives -The objective of this document is to review the existing literature and provide consensus recommendations for veterinary clinicians and lay people on the diagnosis and treatment of dermatophytosis in cats and dogs. Conclusions -No one diagnostic test was identified as the gold standard. Successful treatment requires concurrent use of systemic oral antifungals and topical disinfection of the hair coat. Wood's lamp and direct examinations have good positive and negative predictability, systemic antifungal drugs have a wide margin of safety and physical cleaning is most important for decontamination of the exposed environments. Finally, serious complications of animal-human transmission are exceedingly rare. Methods - Clinical Consensus GuidelinesClinical Consensus Guidelines (CCGs) provide the veterinary community with current information on the pathophysiology, diagnosis and treatment of commonly encountered dermatological conditions. The World Association for Veterinary Dermatology (WAVD) oversees selection of relevant topics, identification of panel members possessing the expertise to draft the Clinical Consensus Guidelines, and any other aspects required to assure the integrity of the process. The statements are derived from evidence-based medicine whenever possible, however when such evidence does not exist then expert opinions would be utilized by the members of the panel. A draft is prepared by the panel, followed by a presentation of the guidelines at major national and/or international veterinary meetings. Access to the guidelines will be available on the WAVD web site. Solicitation for input from WAVD member organizations and affiliate and provisional member groups will result in the incorporation of this feedback into the guidelines. The final CCG manuscript will be submitted to the Veterinary Dermatology journal, where it is reviewed and edited before publication. The authors are solely responsible for the content of the statements.

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Section: Topical Antifungal Treatmentsmentioning

confidence: 74%

Diagnosis and treatment of dermatophytosis in dogs and cats.

Moriello

Coyner²,

Paterson

et al. 2017

Veterinary Dermatology

229

147

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“…These results are in agreement with findings reported by Bismarck et al [52] and Sim et al [56] in otologic canine isolates. This EO, in fact, although poorly effective against molds such as A. fumigatus [49] and dermatophytes [55], showed a strong antimicrobial activity versus Salmonella enterica serotype Typhimurium and Escherichia coli isolated from poultry [50].…”

Section: Discussionmentioning

confidence: 98%

“…This finding is of interest, considering that this EO also appeared active against staphylococci. S. montana has been recently reported as active against M. pachydermatis recovered from canine otitis [52], Candida albicans [53], and Candida glabrata [54] and moderately effective against dermatophytes [55], suggesting a good activity against yeasts.…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial Activity of Essential Oils against Staphylococcus and Malassezia Strains Isolated from Canine Dermatitis

et al. 2020

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Staphylococcus spp. bacteria are the most frequently involved agents in canine cutaneous infections. Treatment of these infections is based on antibiotic therapy, that often is not effective because of the antibiotic-resistance of the bacterial strains. Cutaneous staphylococcal infections are often complicated by Malassezia yeasts, that may be resistant to the conventional antifungal drugs. The present investigation was aimed to evaluate the in vitro antimicrobial activity of some essential oils (EOs) in view of a potential cutaneous application. In detail, EOs obtained from lemon verbena (Aloysia triphylla L’Hèr. Britton), cinnamon (Cinnamomum zeylanicum J. Presl), myrrh (Commiphora myrrha (Nees) Engl. var. molmol), lemongrass (Cymbopogon citratus (DC.) Stapf), litsea (Litsea cubeba (Lour.) Pers.), lemon balm (Melissa officinalis L.), oregano (Origanum vulgare L.), savory (Satureja montana L.), and thyme (Thymus vulgaris L.) were assayed against Staphylococcus spp. and Malassezia pachydermatis strains previously isolated from dogs with dermatitis. All EOs were tested by agar disk diffusion and minimum inhibitory concentration methods to verify the antistaphylococcal activity, and by a microdilution method to evaluate the activity against M. pachydermatis. O. vulgare, T. vulgaris, and S. montana showed the best antibacterial activity against all the selected strains, with MICs ranging from 0.29 to 0.58 mg/mL, from 0.58 to 1.16 mg/mL, and from 0.56 to 1.12 mg/mL, respectively, whereas A. triphylla (1.03 mg/mL) and S. montana (1.8 mg/mL) were the most active against M. pachydermatis. After a proper in vivo evaluation, O. vulgare, T. vulgaris, and S. montana EOs could be a promising treatment to combat canine cutaneous mixed infections.

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“…Helichrysum EO has been extensively studied for its antibacterial and antifungal activities [16] , [17] , which might be involved in its tissue remodeling and anti-proliferative effects and thus contribute to its role in the wound healing process. Ylang ylang EO has been shown to possess antibacterial, antifungal, antioxidant, and anti-inflammatory properties [18] .…”

Section: Discussionmentioning

confidence: 99%

Chemical composition analysis and in vitro biological activities of ten essential oils in human skin cells

Han¹,

Beaumont²,

Stevens³

2017

Biochimie Open

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Research on the biological effects of essential oils on human skin cells is scarce. In the current study, we primarily explored the biological activities of 10 essential oils (nine single and one blend) in a pre-inflamed human dermal fibroblast system that simulated chronic inflammation. We measured levels of proteins critical for inflammation, immune responses, and tissue-remodeling processes. The nine single oils were distilled from Citrus bergamia (bergamot), Coriandrum sativum (cilantro), Pelargonium graveolens (geranium), Helichrysum italicum (helichrysum), Pogostemon cablin (patchouli), Citrus aurantium (petitgrain), Santalum album (sandalwood), Nardostachys jatamansi (spikenard), and Cananga odorata (ylang ylang). The essential oil blend (commercial name Immortelle) is composed of oils from frankincense, Hawaiian sandalwood, lavender, myrrh, helichrysum, and rose. All the studied oils were significantly anti-proliferative against these cells. Furthermore, bergamot, cilantro, and spikenard essential oils primarily inhibited protein molecules related to inflammation, immune responses, and tissue-remodeling processes, suggesting they have anti-inflammatory and wound healing properties. Helichrysum and ylang ylang essential oils, as well as Immortelle primarily inhibited tissue remodeling-related proteins, suggesting a wound healing property. The data are consistent with the results of existing studies examining these oils in other models and suggest that the studied oils may be promising therapeutic candidates. Further research into their biological mechanisms of action is recommended. The differential effects of these essential oils suggest that they exert activities by different mechanisms or pathways, warranting further investigation. The chemical composition of these oils was analyzed using gas chromatography–mass spectrometry.

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In Vitro Activity of Twenty Commercially Available, Plant-Derived Essential Oils against Selected Dermatophyte Species

Cited by 34 publications

References 25 publications

Diagnosis and treatment of dermatophytosis in dogs and cats.

Diagnosis and treatment of dermatophytosis in dogs and cats.

Antimicrobial Activity of Essential Oils against Staphylococcus and Malassezia Strains Isolated from Canine Dermatitis

Chemical composition analysis and in vitro biological activities of ten essential oils in human skin cells

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