In vitroantioxidant and antimicrobial activities of flavonoids fromPanax notoginsengflowers

Abstract

Panax notoginseng and its flowers are both well-known traditional Chinese medicinal herbs. To date, antimicrobial and antioxidant activities of flavonoids from P. notoginseng flowers (PNF) remain unclear. In this study, antimicrobial and antioxidant activities of flavonoids from PNF were investigated. The crude flavonoids were purified using a column (25 cm × 1.5 cm) packed with AB-8 macroporous adsorption resin. Compared with ascorbic acid, the purified flavonoids excelled in scavenging activities on 2,2'-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid, superoxide anion and hydroxyl radicals at 0.2-1.0 mg/mL concentration. However, flavonoids exhibited weaker reducing power than ascorbic acid at 20-100 μg/mL concentration. In addition, the flavonoids exhibited obvious inhibitory effects on Staphylococcus aureus, Aeromonas hydrophila and Pseudomonas aeruginosa. These results clearly indicate that flavonoids from PNF are effective in scavenging free radicals and have the potential to be used as antioxidants and antimicrobial agents, and also provide the theoretical data for supporting the use of PNF in food, pharmaceutical and cosmetics industries.

Comparison of the chromatographic fingerprint, multicomponent quantitation and antioxidant activity of Salvia miltiorrhiza Bge. between sweating and nonsweating

“…Many chronic degenerative diseases and cancer have a direct or indirect relationship with the damaging effects of free radicals (Bielli, Scioli, Mazzaglia, Doldo, & Orlandi, 2015). Medicines possessing antioxidant activity can reduce oxidative stress injury caused by free radicals (Hong, Hu, Liu, Zhou, & Zhao, 2014;Liu & Jiang, 2012;Zhou, Tang, Keep, Ma, & Xiang, 2014). Many components of S. miltiorrhiza Bge.…”

Optimization of Cellulase-Assisted Extraction of Total Flavonoids from Corn Bract and Evaluation of Antioxidant and Antibacterial Aactivities

“…Plant-derived flavonoids have multifold activities and the best described pharmacological activity of flavonoids is to act as potent natural-based antioxidant (Sarian et al, 2017). Moreover, a growing number of articles have demonstrated that antioxidant flavonoids always possess antimicrobial activities in vitro (Erasto et al, 2004;Liu et al, 2010;Hong et al, 2014;de Camargo et al, 2017).…”

Unveiling of Dominant Fungal Pathogens Associated With Rusty Root Rot of Panax notoginseng Based on Multiple Methods

“…Panax notoginseng (Burk.) F. H. Chen, of the family Araliaceae, is a traditional Chinese medicinal plant (Hong et al 2014). Notoginsenoside R1 and ginsenosides Rg1, Rd, Re, and Rb1 are its principal active constituents, which endow a wide range of pharmacological activities, such as anti-inflammatory, antifatigue, and hepato-protection effects, and coronary heart disease prevention (Li et al 2007;Xia et al 2016).…”