<i>In vitro</i>
            Leishmanicidal and antimicrobial activity of fluorinated pyrazoline substituted silicon(IV), zinc(II), cobalt(II) and iron(II) metallophthalocyanines

Aktas Kamıloglu, Ayse; Dırekel, Sahın; Celık, Gonca

doi:10.1080/00958972.2023.2289359

Journal of Coordination Chemistry

2023

DOI: 10.1080/00958972.2023.2289359

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In vitro Leishmanicidal and antimicrobial activity of fluorinated pyrazoline substituted silicon(IV), zinc(II), cobalt(II) and iron(II) metallophthalocyanines

Ayse Aktas Kamıloglu,

Sahın Dırekel,

Gonca Celık

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2024

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Cited by 3 publications

References 46 publications

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Chlorine‐Thymol Substituted Silicon (IV) Phthalocyanines: Synthesis, Characterization, and In Vitro Acetylcholinesterase (AChE)/Butyrylcholinesterase (BChE) Inhibitory Effect

Aktas Kamiloglu,

Arslan,

Tekin

et al. 2024

Applied Organom Chemis

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In this study, novel chlorine‐thymol derivatives (1,3‐bis(4‐chloro‐2‐isopropyl‐5 methylphenoxy)propan‐2‐ol (Thy‐OHI) and 2‐[2‐(4‐chloro‐2‐isopropyl‐5‐methylphenoxy)ethoxy]ethanol (Thy‐OHII)) and axially di‐4‐chloro‐2‐isopropyl‐5‐methylphenoxy (Thy‐SiPc), 1,3‐bis(4‐chloro‐2‐isopropyl‐5‐methylphenoxy)propanoxy (Thy‐OHI‐SiPc), and 2‐[2‐(4‐chloro‐2‐isopropyl‐5‐methylphenoxy)ethoxy]ethanoxy (Thy‐OHII‐SiPc) substituted silicon phthalocyanine compounds were obtained, and their structures were elucidated by the combination of various methods such as NMR, IR, UV–Vis, and MS. The inhibitory effects of these compounds (Thy‐OHI, Thy‐OHII, Thy‐SiPc, Thy‐OHI‐SiPc and Thy‐OHII‐SiPc), synthesized for the first time, on cholinesterase enzymes (AChE and BChE) were investigated in the laboratory environment. In the studies, notably Thy‐OHI‐Si and thymol derivative ligand Thy‐OHII displayed significant inhibition against AChE and BChE.

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Chlorine‐Thymol Substituted Silicon (IV) Phthalocyanines: Synthesis, Characterization, and In Vitro Acetylcholinesterase (AChE)/Butyrylcholinesterase (BChE) Inhibitory Effect

Aktas Kamiloglu,

Arslan,

Tekin

et al. 2024

Applied Organom Chemis

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Investigation of antileishmanial, antioxidant activities, CT-DNA interaction and DFT study of novel cobalt(II) complexes derived from mesogenic aromatic amino acids based Schiff base ligands

Kharpan,

Chetia,

Pyngrope

et al. 2024

Biometals

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Photophysicochemical properties of pyrazoline substituted ZnII-phthalocyanine-based photosensitizers

Yalazan,

Kantekin,

Durmuş

2024

Journal of Organometallic Chemistry

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In vitro Leishmanicidal and antimicrobial activity of fluorinated pyrazoline substituted silicon(IV), zinc(II), cobalt(II) and iron(II) metallophthalocyanines

Cited by 3 publications

References 46 publications

Chlorine‐Thymol Substituted Silicon (IV) Phthalocyanines: Synthesis, Characterization, and In Vitro Acetylcholinesterase (AChE)/Butyrylcholinesterase (BChE) Inhibitory Effect

Chlorine‐Thymol Substituted Silicon (IV) Phthalocyanines: Synthesis, Characterization, and In Vitro Acetylcholinesterase (AChE)/Butyrylcholinesterase (BChE) Inhibitory Effect

Investigation of antileishmanial, antioxidant activities, CT-DNA interaction and DFT study of novel cobalt(II) complexes derived from mesogenic aromatic amino acids based Schiff base ligands

Photophysicochemical properties of pyrazoline substituted ZnII-phthalocyanine-based photosensitizers

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