2011
DOI: 10.3201/eid/1706.100811
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Klebsiella pneumoniaeBacteremia and Capsular Serotypes, Taiwan

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Cited by 20 publications
(13 citation statements)
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“…There have been a few reports with detailed surveillance data on the distribution of capsular serotypes among K. pneumoniae isolates derived from patients with invasive infections across Japan [39]. Our study showed hypervirulent K1 K. pneumoniae is frequently the cause of BSI but is not associated with mortality; similar results have been found in Taiwan and China [40, 41]. It is reported that ESBL-producing isolates are associated with higher mortality rates [42].…”
Section: Discussionsupporting
confidence: 83%
“…There have been a few reports with detailed surveillance data on the distribution of capsular serotypes among K. pneumoniae isolates derived from patients with invasive infections across Japan [39]. Our study showed hypervirulent K1 K. pneumoniae is frequently the cause of BSI but is not associated with mortality; similar results have been found in Taiwan and China [40, 41]. It is reported that ESBL-producing isolates are associated with higher mortality rates [42].…”
Section: Discussionsupporting
confidence: 83%
“…Although most K. pneumoniae strains with the hypermucoviscous phenotype harbored magA , some magA -negative strains harboring the rmpA gene also exhibited this phenotype 32. In the present study, the overall frequency of the hypermucoviscous phenotype was 25.2%, which was similar to those found in other studies33 but higher than those found in other investigations conducted in European countries 34. Interestingly, the identification of virulence genes performed in our study showed that rmpA (10.6%) and magA (6.9%) were present in the hypermucoviscous isolates.…”
Section: Discussionsupporting
confidence: 90%
“…Homology over the entire capsule locus is therefore highest (99% identity) to that of the recently fully sequenced strains CG43 (Accession CP006648), KCTC 2242 (CP002910), and Kp52.145 (FO834906), and also to the partially sequenced capsule biosynthetic loci of VGH525 (Accession AB371296) and Chedid (D21242). The central region of the capsule loci encodes for the antigenic diversity of capsules, which has previously supported the use of PCR as a methodology to identify capsule serotype [40], [41].…”
Section: Resultsmentioning
confidence: 85%