Lactiplantibacillus plantarum ATCC8014 Alleviates Postmenopausal Hypercholesterolemia in Mice by Remodeling Intestinal Microbiota to Increase Secondary Bile Acid Excretion
Shurui Zhang,
Ronghui Liu,
Yuxin Ma
et al.
Abstract:Hypercholesterolemia poses a significant cardiovascular risk, particularly in postmenopausal women. The antihypercholesterolemic properties of Lactiplantibacillus plantarum ATCC8014 (LP) are well recognized; however, its improving symptoms on postmenopausal hypercholesterolemia and the possible mechanisms have yet to be elucidated. Here, we utilized female ApoE-deficient (ApoE −/− ) mice undergoing bilateral ovariectomy, fed a high-fat diet, and administered 10 9 colony-forming units (CFU) of LP for 13 consecu… Show more
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