<i>Measurement of Left Ventricular Output</i>

Peterson, Lysle H.; Helrich, Martin; Greene, Leon; Taylor, Carolyn; Choquette, G

doi:10.1152/jappl.1954.7.3.258

Cited by 31 publications

(10 citation statements)

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“…The two curves differed by less than 10% in area. The results of this study are also in agreement with those of Peterson et al [4] who measured cardiac output in dogs by the rapid injection of dye into the left ventricle through a multi-hole catheter. Dilution curves recorded from the thoracic aorta and the femoral artery yielded cardiac output estimates with a coefficient of variation (SD/mean) of 10.5%.…”

Section: Discussionsupporting

confidence: 92%

A new technique for repeated measurement of cardiac output during cardiopulmonary resuscitation

Geddes

Babbs

1980

Critical Care Medicine

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The authors have developed a method for measurement of cardiac output during CPR with ventricular fibrillation. The method avoids the problems encountered when conventional techniques are used under the conditions of very low cardiac output. The method consists of rapidly injecting 5% saline as the indicator into the left ventricular cavity and detecting its appearance in the descending aorta by withdrawing aortic blood through an electrically calibrated conductivity cell. The adequacy of indicator mixing has been verified by obtaining dilutions curves simultaneously from the brachial and femoral arteries. Cardiac output can be determined even when output is as low as 7 ml/min/kg during CPR with ventricular fibrillation. Repeated determinations can be made as often as every min. This method offers promise as a practical research tool. which can also be used with dye indicators.

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Section: Discussionsupporting

confidence: 92%

A new technique for repeated measurement of cardiac output during cardiopulmonary resuscitation

Geddes

Babbs

1980

Critical Care Medicine

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“…Relatively few investigators [3,4,5,6,7] have used methods which rely on the equilibrium concentration plateau following a con stant rate of indicator infusion. Most feel that the attainment of such an equilibrium concentration is rather dubious because of recirculation.…”

Section: Discussionmentioning

confidence: 99%

Cardiac Output Measurement by Continuous Infusion of Radio Jodinated Sodium Hippurate into the Left Ventricle

Strangfeld¹,

Günther²,

Porstmann³

1969

Cardiology

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“…The first of these requirements is best fulfilled by injecting into the pulmonary artery and sampling from the aortic root (6,7), as was done in these studies. The second requirement is not fulfilled, since flow through the aortic valve is not constant but pulsatile.…”

Section: Discussionmentioning

confidence: 99%

“…A more serious objection is the evidence that the process of mixing of dye with blood in the left atrium is incomplete (4,5), and thus one of the conditions for valid application of the Stewart-Hamilton method is not fulfilled. The interposition of the left ventricle and aortic valve is essential to achieve uniform cross-sectional distribution of indicator at the sampling site (6,7). Therefore, it is necessary to place the tip of the sampling catheter in the aortic root distal to the aortic valve.…”

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confidence: 99%

Evaluation of the Slope-Volume Method as an Index of Pulmonary Blood Volume*

Wang¹,

Shepherd²,

Marshall³

1960

J. Clin. Invest.

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The Stewart-Hamilton method (1) for measurement of blood volumes from indicator dilution curves has been validated in both theory (2) and practice (3), provided that certain conditions are met.Measurement of the pulmonary blood volume by the Stewart-Hamilton method would entail injection of indicator into the main pulmonary artery and sampling from the left atrium. However, while insertion of a catheter into the left atrium of the dog is technically feasible, an unknown portion of the left atrial volume will be included in the measurement. A more serious objection is the evidence that the process of mixing of dye with blood in the left atrium is incomplete (4, 5), and thus one of the conditions for valid application of the Stewart-Hamilton method is not fulfilled. The interposition of the left ventricle and aortic valve is essential to achieve uniform cross-sectional distribution of indicator at the sampling site (6, 7). Therefore, it is necessary to place the tip of the sampling catheter in the aortic root distal to the aortic valve. The blood volume between the site of injection (main pulmonary artery) and the sampling site thus comprises both lungs and the chambers of the left side of the heart. This is probably the nearest approximation to the pulmonary blood volume that can be measured at present by the method.Newman, Pearce and associates (8, 9), using a different analysis of indicator dilution curves, introduced the concept that the "slope volume" provides a measurement or index of the pulmonary blood volume. The slope volume is a func-

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Measurement of Left Ventricular Output

Cited by 31 publications

References 0 publications

A new technique for repeated measurement of cardiac output during cardiopulmonary resuscitation

A new technique for repeated measurement of cardiac output during cardiopulmonary resuscitation

Cardiac Output Measurement by Continuous Infusion of Radio Jodinated Sodium Hippurate into the Left Ventricle

Evaluation of the Slope-Volume Method as an Index of Pulmonary Blood Volume*

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