<i>Measurements of Pulmonary Compliance in Seventy Healthy Young Adults</i>

“…4 Previously, no consistent difference was found in compliance between males and females when subjects of the same size were compared (1) Figure 3.…”

Section: Static Measurementsmentioning

confidence: 89%

“…Photofluorograms of their chests were considered to be "normal." Part of the data on young adults was obtained from previous studies (1,2). Additional measurements were made on a group of young adult volunteers.…”

Section: Methodsmentioning

confidence: 99%

“…In 26 of the elderly subjects, measurements of compliance were made during interrupted breathing starting from the end-expiratory relaxation volume, and compared with similar measurements in a group of 41 younger subjects of the same average height (1 (Figures 2A and 2B). …”

Section: Static Measurementsmentioning

confidence: 99%

“…In a previous study it was found that the elastic properties of lungs appeared to be unaffected by age in healthy adults 17 to 39 years old (1). The slope of the static volume-pressure curve of lungs in the resting tidal range of breathing was used as a measure of pulmonary compliance.…”

mentioning

confidence: 99%

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The Mechanical Behavior of the Lungs in Healthy Elderly Persons12

Frank¹,

Mead²,

Ferris³

1957

J. Clin. Invest.

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250

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In a previous study it was found that the elastic properties of lungs appeared to be unaffected by age in healthy adults 17 to 39 years old (1). The slope of the static volume-pressure curve of lungs in the resting tidal range of breathing was used as a measure of pulmonary compliance. The present study extends observations to adults 50 years and older. To obtain a more complete description of the elastic behavior of lungs, static transpulmonary pressure has been related to the total volume of gas in the lungs, and the range of volume change has been extended from that of tidal volume to inspiratory capacity. In addition, measurement has also been made of pulmonary compliance at various rates of breathing, and of pulmonary flow resistance. Finally, these data have been compared with findings in young adults. MATERIAL AND METHODSEight male and twenty female volunteers, ranging in age from 50 to 89 years, were studied. All were apparently healthy and lived at home. Most of the women did their own housework, while four of the eight men were still employed in office work. They denied any recent or chronic cardiopulmonary disease, and had no untoward shortness of breath. Photofluorograms of their chests were considered to be "normal." Part of the data on young adults was obtained from previous studies (1, 2). Additional measurements were made on a group of young adult volunteers.All measurements were made with the subjects seated. Intraesophageal pressure was used as an index of intrapleural pressure. It was obtained from a thin latex balloon, approximately 15 cm. in length, affixed to polyethylene tubing (3). The balloon was passed to the lower portion of the esophagus. An inductance manometer was used to measure differences in pressure between the esophagus and the mouthpiece (transpulmonary pressure). Pulmonary compliance was measured statically For dynamic measurements of pulmonary compliance, volume changes were measured with a seven-liter capacity Krogh spirometer to which was attached a rotational transducer. The spirometer was connected to a bag-box system (4), enabling the subject to breathe air for periods lasting up to several minutes. Instantaneous flow rate was obtained by electrical differentiation of the volume signal. The three electrical signals (pressure, volume, flow rate) were amplified and transcribed by means of a direct-writing oscillograph.During spontaneous breathing, pulmonary compliance was measured as the ratio of the change in volume (tidal volume) to the change in transpulmonary pressure between instants of zero air flow at the volume extremes of inspiration and expiration. Because variations occurred due to changes in intraesophageal pressure accompanying cardiac contraction, average values for compliance (and flow-resistance) during spontaneous breathing were calculated from at least 20 to 30 measurements.Pulmonary flow-resistance was calculated in two ways. The first method is shown in Figure 1. Points were chosen in both the inspiratory and expiratory phases of a respiratory cycle wh...

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Reference Values for Lung Function in White Children and Adults

Cotes¹

2020

Cotes’ Lung Function

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Measurements of Pulmonary Compliance in Seventy Healthy Young Adults

Cited by 64 publications

References 0 publications

Ventilatory Mechanics in Pulmonary Edema in Man1

Ventilatory Mechanics in Pulmonary Edema in Man1

The Mechanical Behavior of the Lungs in Healthy Elderly Persons12

Reference Values for Lung Function in White Children and Adults

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