<i>Mycoplasma penetrans</i> Bacteremia and Primary Antiphospholipid Syndrome1

Yáñez, Antonio; Cedillo, Lilia; Neyrolles, Olivier; Alonso, E. Blanco; Prévost, Marie‐Christine; Rojas, Jorge; Watson, Harold L.; Blanchard, Alain; Cassell, Gail H.

doi:10.3201/eid0501.990122

Cited by 42 publications

(23 citation statements)

References 13 publications

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“…After 3 days of treatment, the patient improved clinically and was released from the intensive care unit on day 9; thoracic radiographs were clear. [Yáñez et al, 1999]. Mycoplasma penetrans infection was detected in the APS patient's specimens prior to culture and was confirmed by specific polymerase chain reaction (PCR). Similar results were obtained by another pair of PCR primers also within the 16S rRNA gene and designed for the specific detection of Mycoplasma penetrans.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, many clinical criteria for APS have also been well documented in patients with M. pneumoniae infection, including Guillain-Barré-like illness and other central nervous system manifestations, hemolytic anemia, positive Coombs test, thrombocytopenia, and arthritis. [Asherson et al, 1994;Snowden et al, 1990;Yáñez et al, 1999].  Snowden et al (1990) found antiphospholipid antibodies in more than 50% of patients with M. pneumoniae pneumonia, especially those with severe infections requiring hospitalization.…”

Section: Discussionmentioning

confidence: 99%

“…The factor(s) causing production of the antiphospholipid antibodies in primary antiphospholipid syndrome (PAPS) remain unidentified. [Hughes, 1993;Asherson et al, 1994;Yáñez et al, 1999].…”

Section: Antiphospholipid Syndromementioning

confidence: 99%

“…[Grau, et al 1998;Sasaki, et al, 1995] On the other hand, Mycoplasma penetrans infection has also been suggested to be a primary cause of human disease in non-HIV-related urethritis and respiratory disease. [Cordova, et al, 1999;Yáñez et al 1999] The Mycoplasma penetrans HF-2 strain was isolated from a previously healthy HIV-negative patient suffering from severe respiratory distress caused by Mycoplasma penetrans infection-associated systemic disease. [Yáñez et al 1999] The Mycoplasma penetrans HF-2 strain possesses a 1.3 Mb genome, which is the largest among the Mycoplasmataceae species thus far analyzed.…”

Section: Mycoplasma Penetransmentioning

confidence: 99%

“…[Cordova, et al, 1999;Yáñez et al 1999] The Mycoplasma penetrans HF-2 strain was isolated from a previously healthy HIV-negative patient suffering from severe respiratory distress caused by Mycoplasma penetrans infection-associated systemic disease. [Yáñez et al 1999] The Mycoplasma penetrans HF-2 strain possesses a 1.3 Mb genome, which is the largest among the Mycoplasmataceae species thus far analyzed. Sasaki et al, identified 1038 putative coding DNA sequences (CDSs), among which 463 are Mycoplasma penetrans specific.…”

Section: Mycoplasma Penetransmentioning

confidence: 99%

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Presence of Antibodies Against Mycoplasma penetrans in Patients with Antiphospholipid Syndrome

Herrera-Saldivar¹,

Yáñez²,

Bañuelos³

et al. 2012

Antiphospholipid Syndrome

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Antiphospholipid Syndromementioning

confidence: 99%

Section: Mycoplasma Penetransmentioning

confidence: 99%

Section: Mycoplasma Penetransmentioning

confidence: 99%

See 3 more Smart Citations

Presence of Antibodies Against Mycoplasma penetrans in Patients with Antiphospholipid Syndrome

Herrera-Saldivar¹,

Yáñez²,

Bañuelos³

et al. 2012

Antiphospholipid Syndrome

Self Cite

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Higher prevalence of urogenital mycoplasmas in human immunodeficiency virus-positive patients as compared to patients with other sexually transmitted diseases

Córdova

Blanchard²,

Cunha

2000

J. Clin. Lab. Anal.

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We determined the prevalence of three emergent urogenital mycoplasma species (M. fermentans, M. penetrans, and M. genitalium) in comparison to the most common species (M. hominis and U. urealyticum). M. genitalium is probably the third most frequent agent of nongonococcal urethritis (NGU) in men. It has been suggested that M. fermentans and M. penetrans play a role in the development of AIDS. We analysed the urine and the urethral swab samples from 106 HIV‐1 infected individuals (HIV group) and 110 HIV‐negative patients with NGU (STD group) by using PCR and culture methods. M. genitalium was detected in 0.9% of the urine and in 1.9% of the urethral samples from the HIV group, compared to 9.1% found only in urethral swab samples from the STD group. M. fermentans was detected in 5.7% urethral swabs from the HIV group and in 0.9% from the STD group. M. penetrans was detected in 6.6% urine samples from the HIV group. M. hominis and U. urealyticum showed infection rates of 7.5 and 18.9% in the HIV group, and 0.9 and 13.6% in the STD group. Overall there was a higher prevalence of mycoplasmas in the HIV group than in the STD group, but the significance of these results remains unclear. J. Clin. Lab. Anal. 14:246–253, 2000. © 2000 Wiley‐Liss, Inc.

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Mycoplasma

Brown¹,

May²,

Bradbury³

et al. 2015

Bergey's Manual of Systematics of Archaea and Bacteria

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My.co.plas'ma. Gr. masc. n. myces a fungus; Gr. neut. n. plasma something formed or molded, a form; N.L. neut. n. Mycoplasma fungus form. Tenericutes / Mollicutes / Mycoplasmatales / Mycoplasmataceae / Mycoplasma Pleomorphic cells, 300–800 nm in diameter, varying in shape from spherical, ovoid or flask‐shaped, or twisted rods, to slender branched filaments ranging in length from 50 to 500 nm. Cells lack a cell wall and are bounded by a single plasma membrane. Gram‐stain‐negative due to the absence of a cell wall. Some have a complex internal cytoskeleton. Some have a specific tip structure that mediates attachment to host cells or other surfaces. Usually nonmotile , but gliding motility has been demonstrated in some species. Aerobic or facultatively anaerobic . Optimum growth at 37°C is common, but permissive growth temperatures range from 20 to 45°C. Chemo‐organotrophic , usually using either sugars or arginine as the major energy source. Require cholesterol or related sterols for growth. Colonies are usually less than 1 mm in diameter. The typical colony has a fried‐egg appearance . The genome size of species examined ranges from 580 kbp to about 1350 kbp . The codon UGA encodes tryptophan in all species examined. Commensals or pathogens in a wide range of vertebrate hosts. DNA G + C content ( mol %): 23–40. Type species : Mycoplasma mycoides (Borrel, Dujardin‐Beaumetz, Jeantet and Jouan 1910) Freundt 1955, 73 ( Asterococcus mycoides Borrel, Dujardin‐Beaumetz, Jeantet and Jouan 1910, 179).

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Mycoplasma penetrans Bacteremia and Primary Antiphospholipid Syndrome1

Abstract: Mycoplasma penetrans, a rare bacterium so far only found in HIV-infected persons, was isolated in the blood and throat of a non-HIV-infected patient with primary antiphospholipid syndrome (whose etiology and pathogenesis are unknown).

Cited by 42 publications

References 13 publications

Presence of Antibodies Against Mycoplasma penetrans in Patients with Antiphospholipid Syndrome

Presence of Antibodies Against Mycoplasma penetrans in Patients with Antiphospholipid Syndrome

Higher prevalence of urogenital mycoplasmas in human immunodeficiency virus-positive patients as compared to patients with other sexually transmitted diseases

Mycoplasma

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