N-(5-Benzylsulfanyl-1,3,4-thiadiazol-2-yl)-2-(piperidin-1-yl)acetamide

Abstract

Key indicators: single-crystal X-ray study; T = 290 K; mean (C-C) = 0.009 Å; R factor = 0.069; wR factor = 0.217; data-to-parameter ratio = 14.3.The title compound, C 16 H 20 N 4 OS 2 , was synthesized by the reaction of 2-benzylsulfanyl-5-chloroacetamido-1,3,4-thiadiazole and piperidine in a 1:2 ratio. The planes of the acetamide and 1,3,4-thiadiazole units are twisted by 10.8 (4) . The thiadiazole S atom and the acetamide O atom are synoriented due to a hypervalent SÁ Á ÁO interaction of 2.628 (4) Å . In the crystal, molecules form centrosymmetric dimers via N-HÁ Á ÁN hydrogen bonds. These dimers are further connected by C-HÁ Á ÁO interactions into (100) layers. Related literature