N-Benzylhydroxylamine as a novel synthetic block in “C1N1” embedding reaction via α-C(sp³)–H activation strategy

Abstract

A novel process using N-benzylhydroxylamine hydrochloride as a “C1N1 synthon” in [2+2+1] cyclization for the construction of 1,2,5-trisubstituted imidazoles has been described for the first time.