N-Isopropyl-6-methyl-2-phenylquinoline-3-carboxamide

Abstract

In the title compound, C20H20N2O, the dihedral angle between the quinoline ring system and the phenyl ring is 49.40 (5)°. In the crystal structure, zigzag layers of mol­ecules, in which the quinoline units are parallel to the (10) plane, are arranged perpendicular to the b axis. Inter­molecular N—H⋯O hydrogen bonds connect the mol­ecules into chains along [010], reinforcing the cohesion between the layers of the structure.

The synthesis, crystal structure and Hirshfeld analysis of 4-(3,4-dimethylanilino)-N-(3,4-dimethylphenyl)quinoline-3-carboxamide

“…There are two compounds in the database which have an amide group attached to C3, GICGIL [2-chloro-N-(4-fluorophenyl)-6-methylquinoline-3-carboxamide; Govender et al, 2018] and SUZHEB (N-isopropyl-6-methyl-2-phenylquinoline-3-carboxamide; Benzerka et al, 2010). In both these compounds, the amide group is inclined to the quinoline moiety, unlike in molecule 1.…”