Naravelia zeyanica: occurrence of primary benzamides in flowering plants

Jaroszewski, Jerzy W.; Holm-Møller, Søren B.; Jensen, Thomas Høgh; Franzyk, Henrik; Somanadhan, Brinda

doi:10.1080/14786410410001714641

Cited by 13 publications

(9 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…D5-Acetamide, D3-Furfural, D5-furfuryl alcohol for HS-SPME-GC/IDMS were obtained from C/D/N isotopes, Inc. (Pointe-Claire, Quebec, Canada). Vanillamide (3-methoxy,4-hydroxybenzamide) was prepared by treatment of 3-methoxy-4-hydroxybenzonitrile with sodium perborate as previously reported [ 64 ]. Coumaroyl amide and feruloyl amide were synthesized as described previously [ 12 ].…”

Section: Methodsmentioning

confidence: 99%

Controlling microbial contamination during hydrolysis of AFEX-pretreated corn stover and switchgrass: effects on hydrolysate composition, microbial response and fermentation

Serate

Xie

Pohlmann

et al. 2015

Biotechnol Biofuels

View full text Add to dashboard Cite

BackgroundMicrobial conversion of lignocellulosic feedstocks into biofuels remains an attractive means to produce sustainable energy. It is essential to produce lignocellulosic hydrolysates in a consistent manner in order to study microbial performance in different feedstock hydrolysates. Because of the potential to introduce microbial contamination from the untreated biomass or at various points during the process, it can be difficult to control sterility during hydrolysate production. In this study, we compared hydrolysates produced from AFEX-pretreated corn stover and switchgrass using two different methods to control contamination: either by autoclaving the pretreated feedstocks prior to enzymatic hydrolysis, or by introducing antibiotics during the hydrolysis of non-autoclaved feedstocks. We then performed extensive chemical analysis, chemical genomics, and comparative fermentations to evaluate any differences between these two different methods used for producing corn stover and switchgrass hydrolysates.ResultsAutoclaving the pretreated feedstocks could eliminate the contamination for a variety of feedstocks, whereas the antibiotic gentamicin was unable to control contamination consistently during hydrolysis. Compared to the addition of gentamicin, autoclaving of biomass before hydrolysis had a minimal effect on mineral concentrations, and showed no significant effect on the two major sugars (glucose and xylose) found in these hydrolysates. However, autoclaving elevated the concentration of some furanic and phenolic compounds. Chemical genomics analyses using Saccharomyces cerevisiae strains indicated a high correlation between the AFEX-pretreated hydrolysates produced using these two methods within the same feedstock, indicating minimal differences between the autoclaving and antibiotic methods. Comparative fermentations with S. cerevisiae and Zymomonas mobilis also showed that autoclaving the AFEX-pretreated feedstocks had no significant effects on microbial performance in these hydrolysates.ConclusionsOur results showed that autoclaving the pretreated feedstocks offered advantages over the addition of antibiotics for hydrolysate production. The autoclaving method produced a more consistent quality of hydrolysate, and also showed negligible effects on microbial performance. Although the levels of some of the lignocellulose degradation inhibitors were elevated by autoclaving the feedstocks prior to enzymatic hydrolysis, no significant effects on cell growth, sugar utilization, or ethanol production were seen during bacterial or yeast fermentations in hydrolysates produced using the two different methods.Electronic supplementary materialThe online version of this article (doi:10.1186/s13068-015-0356-2) contains supplementary material, which is available to authorized users.

show abstract

Section: Methodsmentioning

confidence: 99%

Controlling microbial contamination during hydrolysis of AFEX-pretreated corn stover and switchgrass: effects on hydrolysate composition, microbial response and fermentation

Serate

Xie

Pohlmann

et al. 2015

Biotechnol Biofuels

View full text Add to dashboard Cite

show abstract

“…Phytochemical and antimicrobial analysis of leaves of N. zeylanica has confi rmed presence of phytosterols which attributes the plant with wound healing and anti-colic properties (Easwaran and Ramani 2011 ). Jaroszewski et al ( 2005 ) have discussed the presence of 3,4-methylenedioxybenzamide, 4-methoxybenzamide and 4-hydroxy-3-methoxybenzamide through ethanolic extraction of leaves, whereas methanolic extracts of leaves show presence of berberine, which is an important alkaloid possessing anticancer and antimicrobial activity and is also used against intestinal infection and diarrhoea.…”

Section: Naravelia Zeylanica DCmentioning

confidence: 99%

Micropropagation: A Boon for Conservation of Valuable Vines and Lianas

Sharma

Shahzad

Akhtar

et al. 2015

Biotechnological Strategies for the Conservation of Medicinal and Ornamental Climbers

View full text Add to dashboard Cite

Woody climbers or lianas are one of the important assets of nature upon which rely many folk and traditional systems of medicine. The increasing need and demand with growing population and thoughtless utilisation of natural products, so far, have resulted into a dwindling population of many plant species. In the present scenario, increasing health issues, hazardous effects of synthetic drugs and thus the preference of natural products over synthetic one, is questioning the survival of many valuable medicinal plant species. Moreover, their own growth pattern, reproductive behaviour and maturation time are the key issues for which fast alternative propagation methods are sought. Advances in the fi eld of biotechnology have opened fresh avenues for replenishment and conservation of such high value plantsplant tissue culture (PTC) or in vitro technique is one among them. In vitro techniques like adventitious shoot regeneration, somatic embryogenesis, bioreactors and fermentation process have speed up regeneration time manyfold. The techniques like protoplast culture, micrografting and genetic transformation have been implied for variety improvement, whereas cryopreservation, slow growth methods and synseed production have been reported for long-term storage of germplasm and their exchange. Thus, PTC justifi es a great deal of contribution in conserving the wealth of nature proving itself a reliable technique in plant biodiversity conservation. Nowadays laudable attempts have been done for the conservation of various useful medicinal climbers through PTC such as Salacia

show abstract

“…In Indian system of medicine ayurveda, it has been used in the treatment of pitta, helminthiasis, dermatopathy, leprosy, rheumatalgia, odontalgia, colic s [10]. The phytoconstituents of NZYM include tannins, flavonoids, phytosterols, alkaloids and terpenoids [11]. Various parts of NZY have been reported to possess various biological activities and proved to have antiinflammatory activity [12], anti-microbial arthritic activity and anti-oxidant activity [14].…”

Section: -490mentioning

confidence: 99%

“…In Indian system of medicine ayurveda, it has been used in the treatment of pitta, helminthiasis, dermatopathy, leprosy, rheumatalgia, odontalgia, colic inflammation, wounds and ulcers [10]. The phytoconstituents of NZYM include tannins, flavonoids, phytosterols, alkaloids and terpenoids [11]. Various parts of NZY possess various biological activities and proved to have anti helminthic, anti-ulcer, anti-inflammato activity [13], anti-arthritic activity and anti Therefore, based on the ethanopharmacological importance, the present study was focused on the evaluation of anti and anti-hyperlipidemic activity of NZYM in STZ model.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of anti-hyperglycemic and anti-hyperlipidemic effects of Naravelia zeylanica in streptozotocin- induced diabetic rats

Rajakalanithi¹,

Swasthika²,

Sujatha³

2017

ijpm

View full text Add to dashboard Cite

Naravelia zeylanica DC (Ranunculaceae), a woody climber, have been used from ancient times to treat various ailments like rheumatoid arthritis, skin diseases, wound and ulcer. The present study was designed to investigate the anti-hyperglycemic activity of methanolic extract of Naravelia zeylanica (NZYM) using experimental diabetic model. Diabetes was induced in wistar rats by a single dose of streptozotocin (55 mg/kg i.p.) (STZ) and treated with NZYM at doses of 100 and 200 mg/kg for 45 days. Glibenclamide (5 mg/kg b.w.) was used as standard drug. Blood glucose and body weight were monitored at regular intervals and the levels of serum insulin, lipid and the carbohydrate metabolic enzyme in the liver were measured at the end of the study. Oral administration of NZYM and glibenclamide significantly reduced the blood glucose level (p<0.05), with increased serum insulin and significant alteration in lipid profiles and liver carbohydrate enzymes (p<0.05) after 45 days. Furthermore, the biochemical parameters correlated with the histopathological changes in the pancreas of STZ-induced diabetic rats, which structurally proved the efficacy of NZYM. The findings suggest that NZYM possess anti-hyperglycemic activity and anti-hyperlipidemic properties and restored STZ-induced pancreatic damage in diabetic rats. NZYM might therefore have a beneficial effect in treatment of diabetes mediated through regulation of carbohydrate metabolic enzyme activities.

show abstract

Naravelia zeyanica: occurrence of primary benzamides in flowering plants

Cited by 13 publications

References 20 publications

Controlling microbial contamination during hydrolysis of AFEX-pretreated corn stover and switchgrass: effects on hydrolysate composition, microbial response and fermentation

Controlling microbial contamination during hydrolysis of AFEX-pretreated corn stover and switchgrass: effects on hydrolysate composition, microbial response and fermentation

Micropropagation: A Boon for Conservation of Valuable Vines and Lianas

Evaluation of anti-hyperglycemic and anti-hyperlipidemic effects of <em>Naravelia zeylanica</em> in streptozotocin- induced diabetic rats

Contact Info

Product

Resources

About