<i>Nocardia cyriacigeorgica</i> brain abscess with Pemphigus vulgaris: first report

Benek, Hüseyin Berk; Akçay, Emrah; Yılmaz, Hakan; Yiş, Reyhan; Yurt, Alaattin

doi:10.1080/02688697.2020.1716943

Cited by 5 publications

(3 citation statements)

References 9 publications

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“…As both can cause lung and CNS involvement, histopathological diagnosis is often needed for definitive diagnosis. Thus a brain tissue biopsy is usually performed, either through a stereotactic brain aspiration or an open brain biopsy of the abscesses 4 5. However, to avoid possible neurological complications from these invasive procedures, we did not proceed with stereotactic aspiration of the brain abscess.…”

Section: Discussionmentioning

confidence: 99%

Case of coexistingNocardia cyriacigeorgicaandAspergillus fumigatuslung infection with metastatic disease of the central nervous system

2022

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Nocardiosis is a rare opportunistic gram-positive bacterial infection. The genus Nocardia consists of non-motile, aerobic, non-spore-forming, catalase-positive, filamentous-branching bacteria with fragmentation into coccoid or bacillary forms. Opportunistic infections due to Nocardia are reported in immunocompromised patients. Aspergillus fumigatus is a conidia forming fungus that can be found in soil, plant matter and dust, causing invasive pulmonary and disseminated infection in immunocompromised patients. Both Nocardia cyriacigeorgica and A. fumigatus are known to cause pulmonary infection with metastatic dissemination to the central nervous system. We present a case of Nocardia and Aspergillus co-infection in a patient who presented within a few days of initiation of immunosuppressants for suspected systemic lupus erythematosus.

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Section: Discussionmentioning

confidence: 99%

Case of coexistingNocardia cyriacigeorgicaandAspergillus fumigatuslung infection with metastatic disease of the central nervous system

2022

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“…Nocardia infection usually occurs due to exogenous inhalation or direct invasion through injured skin; therefore, the lungs and skin are the most common organs involved. Disseminated nocardiosis is frequently seen in immunocompromised patients[ 1 , 11 ], and mortality is high when the brain is involved[ 5 ]. In patients without cellular immune deficiency, the use of systemic glucocorticoids in chronic obstructive pulmonary disease is considered to cause pulmonary nocardiosis[ 1 ].…”

Section: Discussionmentioning

confidence: 99%

“…Nocardia is an opportunistic pathogen, which is frequently seen in immunosuppressed individuals[ 1 - 3 ]. More than 50 Nocardia species have been identified[ 1 , 4 ], including Nocardia asteroides , Nocardia brasiliensis , Nocardia farcinica , and Nocardia otitidiscaviarum , which are the main species causing disease in humans, and Nocardia cyriacigeorgica ( N. cyriacigeorgica ) is a relatively rare pathogen[ 5 ]. N. cyriacigeorgica infection has been reported in organ transplant recipients, long-term glucocorticoid users, and patients with several chronic pulmonary diseases[ 2 , 5 - 8 ].…”

Section: Introductionmentioning

confidence: 99%

Nocardia cyriacigeorgica infection in a patient with pulmonary sequestration: A case report

Lin

Peng

2021

WJCC

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BACKGROUND Nocardia cyriacigeorgica ( N. cyriacigeorgica ) infection is uncommon in clinical practice. Pulmonary sequestration complicated with N. cyriacigeorgica has not been reported in the literature. Here, we present a case of pulmonary se-questration complicated with N. cyriacigeorgica infection in an immunocom-petent woman. CASE SUMMARY A 37-year-old woman complaining of a recurrent cough was admitted to our hospital. Pulmonary sequestration in the lower lobe of the left lung was diagnosed by enhanced computed tomography. Bronchoalveolar lavage fluid was then collected, which showed gram positive bacilli with weakly positive modified acid-fast staining. The pathogen was identified as N. cyriacigeorgica after bacterial culture and mass spectrometry analysis. The patient was diagnosed with pulmonary sequestration complicated with N. cyriacigeorgica infection, and her symptoms quickly improved following anti-infective therapy. CONCLUSION Nocardiosis is considered to be an opportunistic infection. This is the first report of pulmonary sequestration complicated with N. cyriacigeorgica infection in a patient with normal immunity.

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Multiple drug

2023

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Nocardia cyriacigeorgica brain abscess with Pemphigus vulgaris: first report

Cited by 5 publications

References 9 publications

Case of coexistingNocardia cyriacigeorgicaandAspergillus fumigatuslung infection with metastatic disease of the central nervous system

Case of coexistingNocardia cyriacigeorgicaandAspergillus fumigatuslung infection with metastatic disease of the central nervous system

Nocardia cyriacigeorgica infection in a patient with pulmonary sequestration: A case report

Multiple drug

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