2016
DOI: 10.15585/mmwr.mm6523a4
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Notes from the Field:Typhoid Fever Outbreak Associated with an Asymptomatic Carrier at a Restaurant ― Weld County, Colorado, 2015

Abstract: On September 11, 2015, a single case of typhoid fever, caused by Salmonella Typhi infection, was reported to the Colorado Department of Public Health and Environment (CDPHE). Because the patient (patient A) had symptom onset September 2 and had traveled internationally for 4 days 60 days before symptom onset, the case initially was thought to be travel-associated* (1,2). On October 1, a second case of S. Typhi infection was reported in patient B, with symptom onset September 20. Patient B reported no internati… Show more

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Cited by 9 publications
(7 citation statements)
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“…[38][39][40] In fact, because of the potential for lifelong asymptomatic carriage and shedding of Typhi, food handlers may transmit disease to a wide customer base over a prolonged period. [46][47][48][49] Although specific foods, including dairy, ice cream, and fruit and juice, were significantly associated with increased risk of typhoid transmission, we were unable to take into account how these foods were prepared or where they were consumed. We suggest that future casecontrol studies expand on these results by comparing the risks associated with consuming specific foods outside the home versus the risks of consuming those same foods in the home.…”
Section: Discussionmentioning
confidence: 99%
“…[38][39][40] In fact, because of the potential for lifelong asymptomatic carriage and shedding of Typhi, food handlers may transmit disease to a wide customer base over a prolonged period. [46][47][48][49] Although specific foods, including dairy, ice cream, and fruit and juice, were significantly associated with increased risk of typhoid transmission, we were unable to take into account how these foods were prepared or where they were consumed. We suggest that future casecontrol studies expand on these results by comparing the risks associated with consuming specific foods outside the home versus the risks of consuming those same foods in the home.…”
Section: Discussionmentioning
confidence: 99%
“…Ceftriaxone is the drug of choice for treatment of patients with suspected typhoid infection in Ontario, thus the importation of XDR S. Typhi isolates is also a concern because it limits options for empirical treatment. Approximately 5% of patients may shed the bacteria for a long time after resolution of symptoms (13). Therefore, it is essential to identify cases of infection with the XDR strain, particularly individuals who work in the food industry, to ensure that FIG 1 Multiple genome comparison of XDR S. Typhi from this study and the 22420_1_10_Pak60006_2016 strain (GenBank accession no.…”
mentioning
confidence: 99%
“…However, we could not look for H58 in our isolates. This study had a small number of isolates compared to similar outbreak studies of S. typhi [ 13 14 15 ]. Therefore, the data presented are not sufficient to claim that the outbreak may have been associated with other countries' isolates.…”
Section: Discussionmentioning
confidence: 99%