<i>Parathyridaria percutanea</i> and Subcutaneous Phaeohyphomycosis

Rudramurthy, Shivaprakash M; Sharma, Megha; Sethuraman, Nandini; Dutta, Pinaki; Tarai, Bansidhar; Savio, Jayanthi; Bal, Amanjit; Kalawat, Usha; Chakrabarti, Arunaloke

doi:10.3201/eid2509.190383

Cited by 3 publications

(3 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a result, we reviewed 228 published reports. We identified and included 149 reports on 201 cases of dematiaceous fungal infections in SOT recipients 21–169 . The majority (134/149; 90%) of included reports scored ≥ 2 of three possible points on our bias assessment (Table S4).…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Dematiaceous fungal infections in solid organ transplantation: Systematic review and Bayesian meta‐analysis

Radcliffe

Azar

et al. 2022

Transplant Infectious Dis

View full text Add to dashboard Cite

Background: Dematiaceous fungi cause a number of infectious syndromes referred to as phaeohyphomycosis among both immunocompetent and immunocompromised hosts. We performed a systematic review to characterize these infections in solid organ transplant recipients (SOTR). Methods:We searched PubMed database (last searched 1/6/2022) for Englishlanguage reports on dematiaceous fungal infections in SOTR. Included reports needed individualized demographic, treatment, and outcome data; pediatric reports were excluded. A universally applicable bias assessment was performed on reports. Models for infection type and outcome were created using the Bayesian paradigm. Results:We included 149 reports on 201 cases of dematiaceous fungal infections in SOTR. The mean age was 54 years, 72% were men, and kidney recipients accounted for 61% of cases. Skin and soft tissue infection (SSTI) was the most common infectious syndrome (73%). Death from infection occurred in 7% of cases (14/201), with disseminated (32%) cases having the highest mortality. Our model for infection type predicted the relative probability of central nervous system infection to be highest in liver recipients. Across all transplant types, higher relative probabilities of disseminated and pulmonary infections occur in the early post-transplant period, and the predicted probabilities for these infection types decreased after 100 months post-transplantation.Discussion: We identified SSTI as the most common dematiaceous fungal infections in SOTR. Disseminated infections carried the worst prognosis. The evidence in this review is limited by the heterogeneity of included cases. No funding source was used, and this review's protocol was not registered.

show abstract

Section: Resultsmentioning

confidence: 99%

“…An additional 246 cases were identified in 28 reports, but they did not meet our inclusion criteria (Table S5). 9,58,80,140,162,165,170–191 Characteristics of cases included in the present analysis are presented in Table 1. Proven fungal infections accounted for 96% (193/201) of cases, six cases were probable, and two cases were possible.…”

Section: Resultsmentioning

confidence: 99%

Dematiaceous fungal infections in solid organ transplantation: Systematic review and Bayesian meta‐analysis

Radcliffe

Azar

et al. 2022

Transplant Infectious Dis

View full text Add to dashboard Cite

show abstract

“…, are emerging and opportunistic diseases that may infect man and animals. Dematiaceous fungi are characterized by the presence of pale to dark brown melanin-like pigment in their cell walls and live in rotting vegetables, decaying wood, dust and soil [2,3,4].…”

mentioning

confidence: 99%

Phaeohyphomycosis Caused by Cochliobolus hawaiiensis in a Camel Farm in Saudi Arabia: An Emerging Disease

Abdullah

2021

MRJI

View full text Add to dashboard Cite

Phaeohyphomycosis describes subcutaneous lesions caused by dematiaceous fungi, brown-pigmented mould. In a camel farm in Saudi Arabia, the owner complained of cases of skin infection among camels. Lesions persisted after sarcoptic mange outbreak which was treated until the infection resolved. General examination revealed that four camels were affected showing alopecia, erythema, numerous small subcutaneous nodules and brownish blackish crusts. To collect specimens, affected areas were disinfected with 70% ethyl alcohol and deep were taken. Skin scrapings were prepared in 10% potassium hydroxide for microbiological examination. Cultures were done onto Sabouraud dextrose agar (SDA) with chloramphenicol 0.5 mg per ml, incubated at 30⁰C and another set with chloramphenicol 0.5 mg per ml and cycloheximide (Sigma), 0.4 mg/L, incubated at 27⁰C and 37⁰C. Molecular mycology analysis was done by Polymerase Chain Reaction (PCR) on internal transcribed spacer (ITS) gene using ITS1 and ITS4 primers. Microscopic examination indicated it was negative for dermatophytes. It showed brownish to black, septate hyphae arranged as arthro-hyphae, and black yeast-like particles. Cultures yielded multiple, velvety, gray colonies turning brownish black later. Lactophenol cotton-blue smears revealed septate, branched hyphae that are dark brown in colour1.5–5 μ wide. Conidiophores are septate, unbranched with flexuose apexes, bearing brown, multi-septate, cylindrical conidia. ITS gene sequence analysis confirmed the isolate from camel skin scrapings to be Cochliobolus hawaiiensis. The case is interesting as this represents, to the best of our knowledge, the first authenticated report of C. hawaiiensis in animals from a tropical country.

show abstract

Stagonospora cutaneous infection in a kidney transplant recipient: First described case in a human

Celia,

André,

Yanis

2024

Transplant Infectious Dis

View full text Add to dashboard Cite

Parathyridaria percutanea and Subcutaneous Phaeohyphomycosis

Cited by 3 publications

References 10 publications

Dematiaceous fungal infections in solid organ transplantation: Systematic review and Bayesian meta‐analysis

Dematiaceous fungal infections in solid organ transplantation: Systematic review and Bayesian meta‐analysis

Phaeohyphomycosis Caused by Cochliobolus hawaiiensis in a Camel Farm in Saudi Arabia: An Emerging Disease

Stagonospora cutaneous infection in a kidney transplant recipient: First described case in a human

Contact Info

Product

Resources

About