2024
DOI: 10.1002/ardp.202400299
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Peperomia pellucida (L.) Kunth suppresses glycation‐induced inflammatory response in human retinal pigment epithelial cell line ARPE‐19 via JAK‐STAT3 signaling

Keat Lam Ho,
Phaik Har Yong,
Siew Huah Lim
et al.

Abstract: The formation of advanced glycation end product (AGE) is a risk factor for diabetic retinopathy. Since the current treatment for diabetic retinopathy is accompanied by side effects, preliminary findings have suggested Peperomia pellucida (L.) Kunth as a potential alternative therapeutic option for diabetic retinopathy. This study aimed to elucidate the anti‐inflammatory mechanism of P. pellucida in the AGE‐stimulated human retinal pigment epithelial cell line ARPE‐19. Phytochemical analysis revealed phenylpron… Show more

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