2024
DOI: 10.1101/2024.05.02.592193
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Peromyscus leucopus,Mus musculus, and humans have distinct transcriptomic responses to larvalIxodes scapularisbites

Jeffrey S. Bourgeois,
Julie E. McCarthy,
Siu-Ping Turk
et al.

Abstract: Ixodes scapularis ticks are an important vector for at least six tick-borne human pathogens, including the predominant North American Lyme disease spirochete Borrelia burgdorferi. The ability for these ticks to survive in nature is credited, in part, to their ability to feed on a variety of hosts without excessive activation of the proinflammatory branch of the vertebrate immune system. While the ability for nymphal ticks to feed on a variety of hosts has been well-documented, the host-parasite interactions be… Show more

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