<i>Physcomitrella patens</i> MAX2 characterization suggests an ancient role for this F‐box protein in photomorphogenesis rather than strigolactone signalling

López-Obando, Mauricio; Villiers, Ruan de; Hoffmann, Beate; Ma, Linnan; Germain, Alexandre de Saint; Kossmann, Jens; Coudert, Yoan; Harrison, C. Jill; Rameau, Catherine; Hills, P.N.; Bonhomme, Sandrine

doi:10.1111/nph.15214

Cited by 37 publications

(47 citation statements)

References 66 publications

(129 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, where tested, these P. patens proteins do not bind strigolactones [45]. The P. patens MAX2 protein does not obviously act in SL responses [46], but the moss DDK proteins lack some of the key MAX2-interaction residues [29], so if they are SL receptors, this would be consistent with MAX2-independent action. The emergence of the second SMXLC lineage in Bryopsidan mosses is also intriguing; could this represent the convergent evolution of specific SL-targeted SMXL proteins?…”

Section: Discussionmentioning

confidence: 99%

Strigolactone synthesis is ancestral in land plants, but canonical strigolactone signalling is a flowering plant innovation

et al. 2019

View full text Add to dashboard Cite

Background Strigolactones (SLs) are an important class of carotenoid-derived signalling molecule in plants, which function both as exogenous signals in the rhizosphere and as endogenous plant hormones. In flowering plants, SLs are synthesized by a core pathway of four enzymes and are perceived by the DWARF14 (D14) receptor, leading to degradation of SMAX1-LIKE7 (SMXL7) target proteins in a manner dependent on the SCF MAX2 ubiquitin ligase. The evolutionary history of SLs is poorly understood, and it is not clear whether SL synthesis and signalling are present in all land plant lineages, nor when these traits evolved. Results We have utilized recently-generated genomic and transcriptomic sequences from across the land plant clade to resolve the origin of each known component of SL synthesis and signalling. We show that all enzymes in the core SL synthesis pathway originated at or before the base of land plants, consistent with the previously observed distribution of SLs themselves in land plant lineages. We also show that the late-acting enzyme LATERAL BRANCHING OXIDOREDUCTASE (LBO) may be considerably more ancient than previously thought. We perform a detailed phylogenetic analysis of SMXL proteins and show that specific SL target proteins only arose in flowering plants. We also assess diversity and protein structure in the SMXL family, identifying several previously unknown clades. Conclusions Overall, our results suggest that SL synthesis is much more ancient than canonical SL signalling, consistent with the idea that SLs first evolved as rhizosphere signals and were only recruited much later as hormonal signals. Electronic supplementary material The online version of this article (10.1186/s12915-019-0689-6) contains supplementary material, which is available to authorized users.

show abstract

Section: Discussionmentioning

confidence: 99%

Strigolactone synthesis is ancestral in land plants, but canonical strigolactone signalling is a flowering plant innovation

et al. 2019

View full text Add to dashboard Cite

show abstract

“…One possibility is that proteins of the DDK lineage in mosses have evolved to perceive strigolactones (Lopez-Obando et al, 2016), but the current evidence suggests these proteins do not bind strigolactones and that strigolactone signalling in mosses does not utilise the standard MAX2-signalling complex (Bythell-Douglas et al, 2017;Lopez-Obando et al, 2018;Burger et al, 2019). Strigolactone perception in mosses therefore remains enigmatic and might be completely noncanonical (Bennett & Leyser, 2014).…”

Section: The Shadow Of the Past: The D14/kai2 Receptor Familymentioning

confidence: 90%

Fellowship of the rings: a saga of strigolactones and other small signals

2019

View full text Add to dashboard Cite

Strigolactones are an important class of plant signalling molecule with both external rhizospheric and internal hormonal functions in flowering plants. The past decade has seen staggering progress in strigolactone biology, permitting highly detailed understanding of their signalling, synthesis and biological rolesor so it seems. However, phylogenetic analyses show that strigolactone signalling mediated by the D14-SCF MAX2-SMXL7 complex is only one of a number of closely related signalling pathways, and is much less ubiquitous in land plants than might be expected. The existence of closely related pathways, such as the KAI2-SMAX1 module, challenges many of our assumptions about strigolactones, and in particular emphasises how little we understand about the specificity of strigolactone signalling with respect to related signalling pathways. In this review, we examine recent advances in strigolactone signalling, taking a holistic evolutionary view to identify the ambiguities and uncertainties in our understanding. We highlight that while we now have highly detailed molecular models for the core mechanism of D14-SMXL7 signalling, we still do not understand the ligand specificity of D14, the specificity of its interaction with SMXL7, nor the specificity of SMXL7 function. Our analysis therefore identifies key areas requiring further study.

show abstract

“…Current knowledge is based on studies of a few phylogenetically distant species, however, making it difficult to generalize. There is still much to learn about the composition of SLs produced by bryophytes and how SL signalling influences bryophyte body plans, especially given the reports of MAX2 ‐independent signalling in P. patens (Lopez‐Obando et al ., 2018; Figure 3).…”

Section: Strigolactones As a Developmental Regulatormentioning

confidence: 99%

On the outside looking in: roles of endogenous and exogenous strigolactones

2020

View full text Add to dashboard Cite

Summary A collection of small molecules called strigolactones (SLs) act as both endogenous hormones to control plant development and as ecological communication cues between organisms. SL signalling overlaps with that of a class of smoke‐derived compounds, karrikins (KARs), which have distinct yet overlapping developmental effects on plants. Although the roles of SLs in shoot and root development, in the promotion of arbuscular mycorrhizal (AM) fungal branching and in parasitic plant germination have been well characterized, recent data have illustrated broader roles for these compounds in the rhizosphere. Here, we review the known roles of SLs in development, growth of AM fungi and germination of parasitic plants to develop a framework for understanding the use of SLs as molecules of communication in the rhizosphere. It appears, for example, that there are many connections between SLs and phosphate utilization. Low phosphate levels regulate SL metabolism and, in turn, SLs sculpt root and shoot architecture to coordinate growth and optimize phosphate uptake from the environment. Plant‐exuded SLs attract fungal symbionts to deliver inorganic phosphate (Pi) to the host. These and other examples suggest the boundary between exogenous and endogenous SL functions can be easily blurred and a more holistic view of these small molecules is likely to be required to fully understand SL biology. Related to this, we summarize and discuss evidence for a primitive role of SLs in moss as a quorum sensing‐like molecule, providing a unifying concept of SLs as endogenous and exogenous signalling molecules.

show abstract

Physcomitrella patens MAX2 characterization suggests an ancient role for this F‐box protein in photomorphogenesis rather than strigolactone signalling

Cited by 37 publications

References 66 publications

Strigolactone synthesis is ancestral in land plants, but canonical strigolactone signalling is a flowering plant innovation

Strigolactone synthesis is ancestral in land plants, but canonical strigolactone signalling is a flowering plant innovation

Fellowship of the rings: a saga of strigolactones and other small signals

On the outside looking in: roles of endogenous and exogenous strigolactones

Contact Info

Product

Resources

About