<i>Piper guineense</i>(Piperaceae): Chemistry, Traditional Uses, and Functional Properties of West African Black Pepper

Juliani, H. Rodolfo; Koroch, Adolfina R.; Giordano, Luana; Amekuse, L.; Koffa, S.; Asante-Dartey, Julie; Simon, James E.

doi:10.1021/bk-2013-1127.ch003

Cited by 20 publications

(24 citation statements)

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“…HPLC-DAD and UHPLC/Q-TOF MS were used for phytochemical profiling of antibacterial extracts of P. guineense and for the identification of piperamide alkaloids in Piper guineense . Our HPLC-DAD data indicates that piperamide alkaloids are the predominant compounds in P. guineense hexane, methanol, ethanol and chloroform extracts (Figure 1) and these compounds are suggested to be responsible for the antibacterial effects we have observed for this plant in agreement with other authors [7,34]. For proper identification and characterization of the piperamide alkaloids, a hexane extract of the leaf was chosen.…”

Section: Resultssupporting

confidence: 89%

Alkaloid-Rich Crude Extracts, Fractions and Piperamide Alkaloids of Piper guineense Possess Promising Antibacterial Effects

et al. 2018

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Piper guineense is a food and medicinal plant commonly used to treat infectious diseases in West-African traditional medicine. In a bid to identify new antibacterial compounds due to bacterial resistance to antibiotics, twelve extracts of P. guineense fruits and leaves, obtained by sequential extraction, as well as the piperine and piperlongumine commercial compounds were evaluated for antibacterial activity against human pathogenic bacteria. HPLC-DAD and UHPLC/Q-TOF MS analysis were conducted to characterize and identify the compounds present in the extracts with promising antibacterial activity. The extracts, with the exception of the hot water decoctions and macerations, contained piperamide alkaloids as their main constituents. Piperine, dihydropiperine, piperylin, dihydropiperylin or piperlonguminine, dihydropiperlonguminine, wisanine, dihydrowisanine and derivatives of piperine and piperidine were identified in a hexane extract of the leaf. In addition, some new piperamide alkaloids were identified, such as a piperine and a piperidine alkaloid derivative and two unknown piperamide alkaloids. To the best of our knowledge, there are no piperamides reported in the literature with similar UVλ absorption maxima and masses. A piperamide alkaloid-rich hexane leaf extract recorded the lowest MIC of 19 µg/mL against Sarcina sp. and gave promising growth inhibitory effects against S. aureus and E. aerogenes as well, inhibiting the growth of both bacteria with a MIC of 78 µg/mL. Moreover, this is the first report of the antibacterial activity of P. guineense extracts against Sarcina sp. and E. aerogenes. Marked growth inhibition was also obtained for chloroform extracts of the leaves and fruits against P. aeruginosa with a MIC value of 78 µg/mL. Piperine and piperlongumine were active against E. aerogenes, S. aureus, E. coli, S. enterica, P. mirabilis and B. cereus with MIC values ranging from 39–1250 µg/mL. Notably, the water extracts, which were almost devoid of piperamide alkaloids, were not active against the bacterial strains. Our results demonstrate that P. guineense contains antibacterial alkaloids that could be relevant for the discovery of new natural antibiotics.

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Section: Resultssupporting

confidence: 89%

Alkaloid-Rich Crude Extracts, Fractions and Piperamide Alkaloids of Piper guineense Possess Promising Antibacterial Effects

et al. 2018

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“…Piper guineense SCHUMACH.., a spice plant from the class Magnoliopsida, order Piperales and family Piperaceae, is an important plant that has culinary, medicinal, cosmetic and insecticidal uses (JULIANI et al 2013, BESONG et al 2016. The plant is found in tropical regions of central and west Africa, where it is semi-cultivated in countries like Nigeria, especially in the southern parts (PURSEGLOVE et al 1981).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Piper guineense Schumach. seed powder in the control of Callosobruchus maculatus (Fabricius, 1775) (Coleoptera: Chrysomelidae: Bruchinae) and on the nutritional and organoleptic characteristics of stored cowpea Vigna unguiculata (L.) Walp.

Ojiako¹,

Adesiyun²,

Ihejirika³

et al. 2018

Polish Journal of Entomology

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Brown pepper (Piper guineense) seed powder, used for culinary and medicinal purposes, was evaluated in the laboratory with a conventional storage chemical, actellic 2% dust (Pirimiphos-methyl), as standard, to protect stored cowpea against the cowpea bruchid, Callosobruchus maculatus. Four rates of the seed powder were used (2.5, 5.0 and 10.0 g/100 g seed with a control, 0.0 g) while actellic dust was applied at 1.0, 2.0, 3.0 g/100 g seed and 0.0 g/100 g seed as control. Data on percentage mortality, oviposition, adult emergence and seed damage were collected over a six-month period. Weevil perforation indexes (WPI) were estimated with the seed damage data. All data were analysed for variance at P≤0.05. Actellic dust at the lowest dose inflicted adult mortality (90 – 100%) in the first 48 h after treatment and prevented oviposition (95 – 100%) in the first five months of storage compared to the control. The highest rate of Piper guineense application caused mortality of up to 90.0% in 48 h, reduced oviposition (70 – 80%), decreased adult emergence (15.90 to 28.40 insects) as against the control (104.7 – 272.7 insects) and reduced seed damage by 80 % with a WPI of between 33.3 and 10.0 %. Proximate analysis and germination tests indicated that the treatment materials increased the moisture and crude fibre content, decreased crude protein content but had no significant effect on the viability of stored seeds. Organoleptic tests demonstrated that treatment materials had no significant negative effect on taste, odour, texture, appearance and overall acceptability of cooked cowpea seeds after six months of storage. It can be safely concluded that the powdered form of P. guineense seed at the highest doses (5.0 and 10.0 g) gave significant protection of cowpea seeds against the cowpea bruchid, which compared favourably with actellic dust when applied topically.

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“…Author(s) agree that this article remains permanently open access under the terms of the Creative Commons Attribution License 4.0 International License natural products including volatiles oils, lignans, amides, alkaloids, flavonoids and polyphenols (Rodolfo et al, 2013). The leaves and seeds are usually sold in Nigerian markets as an edible medicinal plant or additive in foods to offer aroma and flavor.…”

Section: Introductionmentioning

confidence: 99%

Volatile compound analysis of the leaves and seeds of Piper guineense using gas chromatography-mass spectrometry (GC-MS)

Ojinnaka¹,

Ubbor²,

Okudu³

et al. 2016

Afr. J. Food Sci.

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The volatile compounds in the leaves and seeds of Piper guineense plant from South East Nigeria, were investigated using gas chromatography-mass spectrometry (GC-MS). The analysis was carried out to identify the compounds responsible for the characteristic flavor of the flavouring spices. A total of thirty-three volatile constituents were identified in the leaves and seeds of Piper guineense using GC-MS. The major compounds identified include acids, esters, alcohols, hydrocarbons and others. Acids were found to be the predominant constituent group followed by esters. The leaves and seeds of Piper guineense had acids in the values of 65.56 and 53.72%, respectively. The esters were also found to be more in the leaves (25.63%) than in the seeds (5.22%) of P. guineense. The hydrocarbons identified appeared more in the seeds (11.47%) of P. guineense. The monoterpene (beta-myrcene) and sesquiterpenes (aromadendrene, trans-alpha-bergamotene, copaene) hydrocarbons identified were also present in the seeds than in the leaves of the P. guineense. Gamma-elemene, a sesquiterpene were identified in both the leaves and seeds of P. guineense at the same retention time of 10.242 min but at different concentrations of 0.41 and 0.72%, respectively.

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Piper guineense(Piperaceae): Chemistry, Traditional Uses, and Functional Properties of West African Black Pepper

Cited by 20 publications

References 71 publications

Alkaloid-Rich Crude Extracts, Fractions and Piperamide Alkaloids of Piper guineense Possess Promising Antibacterial Effects

Alkaloid-Rich Crude Extracts, Fractions and Piperamide Alkaloids of Piper guineense Possess Promising Antibacterial Effects

Efficacy of Piper guineense Schumach. seed powder in the control of Callosobruchus maculatus (Fabricius, 1775) (Coleoptera: Chrysomelidae: Bruchinae) and on the nutritional and organoleptic characteristics of stored cowpea Vigna unguiculata (L.) Walp.

Volatile compound analysis of the leaves and seeds of Piper guineense using gas chromatography-mass spectrometry (GC-MS)

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