We present a tomographic velocity and anisotropy model of the uppermost mantle beneath the Tibetan Plateau and the adjacent regions. The investigation analyzed 105,385 P n phase readings from the International Seismological Centre (ISC) and the China Earthquake Data Center. The average P n velocity under the study area is approximately 8.15 km/s, with velocity perturbations up to 3-4%. We find high P n velocities under the Indian Plate and in the Tarim and Sichuan basins, low P n velocities under the Hindu Kush and in Myanmar and the adjacent region, and especially low P n velocities under the area north of the Indus-Yarlung Zangbo suture. The high P n velocity anomalies of the Indian Plate are discontinuous at the collision region in the east-west direction, indicating that the Indian Plate probably subducts in a piecewise manner. Distributions of P n velocities are used to validate mechanisms for the subduction of the Indian Plate presented in previous studies. In addition, P n anisotropy is obtained simultaneously with P n velocity. At plate collision zones, the fast P n anisotropy direction is parallel to the direction of the collision edge. We validate the existence of P n anisotropy under these regions and discuss the relationship of anisotropy with tectonic structure and plate movement.