Podophyllum hexandrum ameliorates endosulfan-induced genotoxicity and mutagenicity in freshwater cyprinid fish crucian carp

Abstract

This study confirms the antimutagenic potential of the subject plant with the identification of some novel compounds, justifying their use in folk medicine, and their corresponding benefit to mankind.

Using a Dynamic Time Series Model (Arima) for Forecasting of Egyptian Cotton Crop Variables

“…Its high-ranking medicinal significance is attributed to active compounds such as podophyllotoxin or podophyllin (neurotoxin), its glycosides, epipodophyllotoxin, podophyllotoxone, podophyllic acid and anti-mutagenic. Podophyllotoxin is a precursor of etoposide (Vepeside), approved anticancer drug by food and drug administration (FDA) and semi-synthetic topoisomerase inhibitors which are used to treat testicular and lung cancer (Giri and Narasu, 2000;Qazi et al, 2011;Dar et al, 2017). Podophyllotoxin derived pesticides are used to control crop attacking insect pests (Yang et al, 2017).…”

IRRIGATION SCHEDULES AND PLANTING MODES impact ON FARMLAND MICROCLIMATE AND DRY MATTER ACCUMULATION OF WINTER WHEAT

“…Its high-ranking medicinal significance is attributed to active compounds such as podophyllotoxin or podophyllin (neurotoxin), its glycosides, epipodophyllotoxin, podophyllotoxone, podophyllic acid and anti-mutagenic. Podophyllotoxin is a precursor of etoposide (Vepeside), approved anticancer drug by food and drug administration (FDA) and semi-synthetic topoisomerase inhibitors which are used to treat testicular and lung cancer (Giri and Narasu, 2000;Qazi et al, 2011;Dar et al, 2017). Podophyllotoxin derived pesticides are used to control crop attacking insect pests (Yang et al, 2017).…”