Prosopis nigra Mesocarp Fine Flour, A Source of Phytochemicals with Potential Effect on Enzymes Linked to Metabolic Syndrome, Oxidative Stress, and Inflammatory Process

Abstract

Pods of P. nigra are traditional food resources in South America. The non-conventional flour obtained from them is a food that inhibits enzymes linked to carbohydrates metabolism and lipids metabolism, show antioxidant activity and anti-inflamatory activity, principally on COX-2. This natural product is a promising resource that could be used as a functional food or as functional ingredient in food formulations for reduce the risk of the development of obesity. Our studies are relevant to stimulate a sustainable management of this specie and for its development as potential new crops.

Biocompatible and Biodegradable Electrospun Nanofibrous Membranes Loaded with Grape Seed Extract for Wound Dressing Application

“…Several mathematical models have been used for studying the drug release profile from distinct polymer matrices [49]. Among them, the Korsmeyer-Peppas model (see equation (4) in Experiment) is widely used, since it can describe in a straightforward way the drug release profile from a polymeric system. This model categorizes release profiles based on the value of n exponent [35].…”

“…Natural bioactive phenolic compounds have gained much importance in the past years for promoting health or preventing disease due to their beneficial physiological properties, including antioxidant [1][2][3], anti-inflammatory [4,5], anticarcinogenic [6][7][8], and antimicrobial activities [3,8]. Sources for obtaining polyphenolic compounds are varied, including byproducts and wastes generated by agroindustry [9], which can be used, for instance, as food antioxidants and antimicrobial agents [10].…”

Phenolic compounds and bioactivity evaluation of aqueous and methanol extracts ofAllium mongolicumRegel

“…It was indicated that the extracts that contains high amount of polyphenolic obtained from herbs had effects in modulating the activity of selected digestive enzymes, such as lipase, a-glucosidase, and angiotensin-converting enzyme (ACE) (Sakulnarmrat & Konczak, 2012). Natural products may play a vital role in blocking the occurrence and development of many chronic diseases such as obesity, diabetes, and hypertension through regulating of various trails, including intestinal catabolism of complex carbohydrates and fat absorption (Perez, Zampini, Alberto, & Isla, 2018).…”

Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence

“…Similarly, Vasile et al evaluated the toxicity effects of Pal gum, and there was no side effect under in vitro condition; thus concluding that Pal gum is a safe, functional food additive with admired impacts for human health [11]. In another study [117], the clinical effectiveness of P. nigra (Pni) for food and pharmacological industries has extensively investigated, and the results suggested that the flour of these tree has the potential to decline the complications associated with metabolic syndromes, oxidative stress, and inflammatory responses. The researchers declared that the Pni natural products are new sources of functional foods with beneficial effects for improving the health quality of the human body [117].…”

“…In another study [117], the clinical effectiveness of P. nigra (Pni) for food and pharmacological industries has extensively investigated, and the results suggested that the flour of these tree has the potential to decline the complications associated with metabolic syndromes, oxidative stress, and inflammatory responses. The researchers declared that the Pni natural products are new sources of functional foods with beneficial effects for improving the health quality of the human body [117]. More than 200 studies sporadically reported the significant results of Prosopis genus (especially Pci), and these studies highlighted the efficacy of these species for commercialization to derive functional products for improving the complications of daily maladies [118].…”