Psidium guajavaderived carbon nanoparticles: A promising red emissive cellular bioimaging agent

Abstract

We report a simple, cost-effective, microwave-assisted green synthesis route of red-emitting fluorescence carbon nanoparticles (CNPs) using Psidium guajava (Guava leaves). The synthesis of CNPs is a simple, affordable, and rapid method of producing carbon nanoparticles. The CNPs were characterized by various spectroscopic and microscopic techniques. Atomic force microscopy studies showed that the average size of CNPs is approximately 50 nm. The CNPs exhibited excellent photoluminescence properties with a maximum emission at 677 nm, making them suitable for bioimaging applications. The Ionic, photostability, and thermal stability of CNPs were also checked to understand their robustness. Retinal pigment epithelium (RPE) cells were exposed to these nanoparticles and showed very efficient uptake, some fraction of it also getting targeted to the nucleus, indicating that CNPs are non-toxic and biocompatible for future biological experiments. The results indicate that guava leaves can be a promising source for the synthesis of red emissive CNPs through the very simple method of synthesis and with bioimaging applications.

Red fluorescent carbon nanoparticles derived from Spinacia oleracea L.: a versatile tool for bioimaging and biomedical applications

“…The main benefit of employing microwave heating is the uniform, non-contact heat transfer to the solution, and its penetration characteristics enable the reactions to occur swiftly. 20 The microwave method is a highly effective procedure for nanoparticle synthesis, owing to its numerous benefits, such as being non-toxic, straightforward, scalable, and cost-effective. Nevertheless, the primary drawback of this technique is the limited ability to control the size of the resulting nanoparticles precisely.…”

Azadirachta indica:derived, red-emitting, carbon nanoparticles for cellular bioimaging and potential therapeutics

“…16 For the synthesis of fluorescent carbon nanoparticles (CNPs), a variety of precursor materials are employed; however, due to their affordability, environmental friendliness, and tuneable fluorescent CNPs, the uses of CNPs in bioimaging, sensing drug delivery, catalysis, photovoltaics, and other fields are expanding. 17 The fluorescence characteristics of CNPs under ultraviolet (UV) irradiation are their most distinctive features.…”

“…7 Psidium guajava (Guava) was used to derive red fluorescence carbon nanoparticles (CNPs) by microwave-assisted method. 17 The roseheart radish showed blue luminescence under UV light at 365nm. 25 The three fluorescent carbon nanoparticles (FCP) were synthesized by mango fruit.…”