<i>Pteolopsis suberosa</i> Engl. et Diels (Combretaceae) : une plante à activité antiulcère et anti <i>Helicobacter pylori</i>

Sanogo, Rokia

doi:10.4267/2042/53781

Cited by 4 publications

(4 citation statements)

References 5 publications

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“…On the other hand, the high cost of health services and drugs, as well as socio-economic factors, are causing a large part of the population to use medicinal plants for treatment [10,11,12,13,14,15,16,17]. Despite these many virtues and the growing interest of the rural population in this species for health care, there are no (to our knowledge) data on the assessment of the antioxidant potential of Datura species encountered in Mali.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of in vitro Antioxidant Activities of Ethanol Extracts of Datura innoxia Mill. Leaves and Seeds Harvested in Mali

Togola

Dembélé

Tounkara

et al. 2019

ARRB

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Aims: The purpose of this study was to evaluate the in vitro antioxidant activities of Datura innoxia Mill. leaves and seeds harvested in Mali. Place and Duration of Study: Collection of plant materials were done at Kolondieba (Mali) in june 2016. Evaluation of polyphenols and flavonoids contents, determination of antioxidant activities were done at Laboratory of Plant and Food Biochemistry and Biotechnology of University of Sciences, Techniques and Technologies of Bamako (Mali) between august 2016 and March 2017. Methodology: The leaves and seeds were collected in Kolondieba, Mali. The phytochemical screening based on the standard methods of tube reactions has been performed with ethanol extracts. The quantitative estimation of total polyphenols was made by the Folin-Ciocalteu method and that of flavonoids by the use of aluminum trichloride. The in vitro antioxidant activities of the ethanol extracts was determined by three methods: the 1,1- diphenyl - 2- picrylhydrazyl (DPPH) test, the ferric reducing ability power (FRAP) test and the Phosphomolybdate test (PPM). Results: The phytochemical screening revealed that leaves and seeds of this plant contains alkaloids, polyphenols, flavonoids, coumarins, tannins, triterpenes and saponin. Phenolic contents of ethanol extracts are 30.97 ± 0.33 mg equivalent gallic acid / g in leaves and 14.02 ± 0.15 mg equivalent gallic acid / g in seeds; those of flavonoids are 15.13 ± 0.2 mg equivalent of quercetin / g in the leaves and 4.93 ± 0.41 mg equivalent of quercetin / g in the seeds. The three tests showed that the leaves have a higher level of antiradical activity in vitro than seeds. Conclusion: The results of this work showed that Datura innoxia Mill. has a good antioxidant activity which would justify its use as a potential source of natural antioxidants.

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Section: Introductionmentioning

confidence: 99%

Evaluation of in vitro Antioxidant Activities of Ethanol Extracts of Datura innoxia Mill. Leaves and Seeds Harvested in Mali

Togola

Dembélé

Tounkara

et al. 2019

ARRB

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“…In other side, to face up the resurgence of antimicrobial-resistant pathogens, the researchers worldwide are hardworking to find other alternative sources of drugs and bioactive chemical compounds of plant origin [3] that would serve as antimicrobial agents less expensive, less toxic, and more effective [4]. This is why, many plants have been explored as alternative sources of drugs and in particular antimicrobial and anti-inflammatory agents [5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activities of Extracts from four Wild Food Fruits

Konaré

Keita²,

Somda³

et al. 2023

EJNFS

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Aims: This study aimed to assess the in vitro antibacterial effects of extracts from four wild food fruits: Balanites aegyptiaca, Saba senegalensis, Ziziphus mauritiana, and Raphia sudanica. Place and Duration of Study: The samples of plant material were collected at Banamba and Sikasso, Mali between January and May 2018. The bacterial strains were collected at Research Centre for Biological Food and Nutritional Sciences (CRSBAN), University Professor Joseph Ki-Zerbo; Ouagadougou, Burkina Faso. The experimental parts were also carried out at CRSBAN from October 2019 to January 2020. Methodology: The fruit extracts were screened for antibacterial activity against Escherichia coli, Salmonella typhi, S. aureus, B. cereus, and L. monocytogenes strains. The diameters of the inhibition zones (ID), the minimum inhibitory concentrations (MIC) as well as the minimum bactericidal concentrations (MBC) were evaluated using agar diffusion method. Results: The findings revealed that these parameters have varied as a function of fruit species and/or their zones of provenances. All fruit extracts showed significant growth reducing effect against all the tested bacteria. The extracts from R. sudanica have exhibited the strongest growth-inhibiting activity specifically against E. coli (ID = 15.33±0.58 mm) and Salmonella typhi (ID = 18.00±1.00 mm) with lower MIC (from 2.08±1.44 to 5.83±1.44 mg/mL). Moreover, the MBC/MIC ratios revealed that the extracts from the studied fruits possess mainly bacteriostatic effects towards the tested strains. Conclusion: These findings support local therapeutics properties attributed to these fruits. They also demonstrate that, in addition to their nutritional values, these edible fruits could be used for developing antibiotics to treat infectious diseases and food poisoning.

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“…There is therefore a great need to find alternative sources of bioactive chemicals, in particular of plant origin which can readily be used though undergoing an extensible manufacturing process (Biyiti et al, 2004). In recent years, many plants have been investigated as alternative sources of bioactive drugs and in particular antimicrobial agents (Sanogo, 2014;Haidara et al, 2016;Akhtar et al, 2018;Bagayoko et al, 2018;Haidara, 2018;Keita et al, 2018;Mihin et al, 2019). Traditional plant-based medicine remains the first option for treatment in low-income countries.…”

Section: Introductionmentioning

confidence: 99%

“…These discoveries could yield to unknown bioactive molecules that could be useful for the treatment of diseases and the standardisation of therapeutic compositions (Haidara, 2018). In Mali, the National Institute of Research in Public Health (INRSP) through its Department of Traditional Medicine (DMT), a structure specializing in the exploration and development of phytomedicines, has carried out numerous studies to this end (Diallo et al, 2003;Willcox et al, 2007;Togola et al, 2008;Sanogo et al, 2012;Sanogo et al, 2014;Haidara et al, 2016;Traoré et al, 2019;Denou et al, 2019). However, many other plant species commonly used by local populations have not yet been explored.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the biological activities of leaf and bark extracts of Ficus platiphylla Delile, a medicinal plant used in Mali

KonarÃ¹,

Diarra²,

CissÃ³

et al. 2020

J. Med. Plants Res.

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Leaves and barks of Ficus platiphylla are used in traditional medicine in western Africa for treating bacterial infections. The aim of this work was to screen the biological activities of extracts of the plant. Three common bacterial strains were used in this study. The antiradical and antibacterial activities were assessed respectively by spectrophotometric and agar diffusion methods. The bark and leaves are very rich in dry matter, ash and as well as proteins and carbohydrates. Ethyl acetate was the best solvent to extract polyphenols (4.77-5.01 g/100 g) and flavonoids (1.97-3.32 g/100 g). Similarly, ethyl acetate extracts showed the best anti-free radical activity with IC 50 = 5.10 and 5.22 µg/ml for bark and leaves respectively. The aqueous and methanolic leaf extracts displayed the highest antibacterial activity on the Escherichia coli, with an inhibition diameter (ID) of 11.50 ± 0.50 mm. On Salmonella typhi, the most active antibacterial agents were found in leaf ethyl acetate extracts with ID = 15.33 ± 0.58 mm. These extracts have the same efficacy as the commercial antibiotic ciprofloxacin (positive control) which displayed an ID of 15.33 ± 0.76 mm. Finally, S. aureus was highly sensitive to ethyl acetate extracts of the barks: ID = 15.50 ± 1.32 mm (p-value = 4.10E-6 < 0.05). The richness in secondary metabolites associated with the antiradical and antibacterial activities justify use of F. platiphylla in traditional medicine. This study shows that F. platiphylla could be a valuable medicinal plant for the management of common bacterial infections.

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Pteolopsis suberosa Engl. et Diels (Combretaceae) : une plante à activité antiulcère et anti Helicobacter pylori

Cited by 4 publications

References 5 publications

Evaluation of in vitro Antioxidant Activities of Ethanol Extracts of Datura innoxia Mill. Leaves and Seeds Harvested in Mali

Evaluation of in vitro Antioxidant Activities of Ethanol Extracts of Datura innoxia Mill. Leaves and Seeds Harvested in Mali

Antibacterial Activities of Extracts from four Wild Food Fruits

Evaluation of the biological activities of leaf and bark extracts of Ficus platiphylla Delile, a medicinal plant used in Mali

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