Quercus salicina Blume: Research Progress in Chemistry and Pharmacodynamics (1959–2021)

Abstract

The crude extracts of different parts (leaves and shoots) of Quercus salicina Blume (QS) have shown considerable effect in urolithiasis. QS has been widely used in clinical practice and has attracted great research interest The relevant published literature, however, reveals only partial education of its chemical components and bio-active mechanisms, and only two review articles have summarized the QS research progress. In this review, a comprehensive and systematic review of chemistry and pharmacodynamics of QS was carried out using the international authoritative databases (1959-2021), focusing on phenols and flavonoids, and their effect such as urinary stone dissolution, anti-inflammatory, anti-diabetes, anti-bacterial, antioxidant, and anti-allergy activities as well as toxic effects. The aim of review is to provide the most recent and effective literature support for further basic research and application development.

Protective effects of Quercus salicina blume leaves aqueous extracts against cadmium-induced oxidative stress and cell cytotoxicity in HK-2 cells

“…Quercus salicina Blume, native to Korea and Japan, is known to have health-promoting attributes including antioxidant, anti-inflammatory, antibacterial, antiedema, stone dissolving, and diuretic properties [15,16]. This study had two main objectives.…”

“…Sustained inflammation, commonly termed chronic inflammation, may contribute to the development of conditions such as atherosclerosis, rheumatoid arthritis, inflammatory bowel disease, and even diabetes [14]. Quercus salicina Blume is known to possess various phytochemicals and thus reported to have anti-oxidative, anti-inflammatory, anti-hemolytic, and anti-cancer effects [15,16]. Quercus (oak) trees have been widely utilized for medicinal purposes due to the medicinal properties of their leaves, bark, and fruit [17].…”

“…Quercus (oak) trees have been widely utilized for medicinal purposes due to the medicinal properties of their leaves, bark, and fruit [17]. They have been traditionally used to treat burns, hemorrhage, and gastrointestinal diseases, such as dysentery [16]. This study aims to evaluate the antioxidant effects of Quercus salicina Blume leaves and its protective effects against cadmium-induced oxidative stress and apoptosis, which cause kidney cell damage.…”