RehaBEElitation: the architecture and organization of a serious game to evaluate motor signs in Parkinson’s disease

Abstract

Background The use of serious games (SG) has received increasing attention in health care, and can be applied for both rehabilitation and evaluation of motor signs of several diseases, such as Parkinson’s disease (PD). However, the use of these instruments in clinical practice is poorly observed, since there is a scarcity of games that, during their development process, simultaneously address issues of usability and architectural design, contributing to the non-satisfaction of the actual needs of professionals and patients. Thus, this study aimed to present the architecture and usability evaluation at the design stage of a serious game, so-called RehaBEElitation, and assess the accessibility of the game. Methods The game was created by a multidisciplinary team with experience in game development and PD, taking into consideration design guidelines for the development of SG. The user must control the movements of a bee in a 3D environment. The game tasks were designed to mimic the following movements found in the gold-standard method tool—Movement Disorder Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS)—for the assessment of individuals with PD: hand opening and closing, hand extension and flexion, hand adduction and abduction, finger tapping, and forearm supination and pronation. The user interacts with the game using a wearable interface device that embeds inertial and tactile sensors. The architecture of RehaBEElitation was detailed using the business process model (BPM) notation and the usability of the architecture was evaluated using the Nielsen-Shneiderman heuristics. Game accessibility was evaluated by comparing the overall scores of each phase between 15 healthy participants and 15 PD patients. The PD group interacted with the game in both the ON and OFF states. Results The system was modularized in order to implement parallel, simultaneous and independent programming at different levels, requiring less computational effort and enabling fluidity between the game and the control of the interface elements in real time. The developed architecture allows the inclusion of new elements for patient status monitoring, extending the functionality of the tool without changing its fundamental characteristics. The heuristic evaluation contemplated all the 14 heuristics proposed by Shneiderman, which enabled the implementation of improvements in the game. The evaluation of accessibility revealed no statistically significant differences (p < 0.05) between groups, except for the healthy group and the PD group in the OFF state of medication during Phase 3 of the game. Conclusions The proposed architecture was presented in order to facilitate the reproduction of the system and extend its application to other scenarios. In the same way, the heuristic evaluation performed can serve as a contribution to the advancement of the SG design for PD. The accessibility evaluation revealed that the game is accessible to individuals with PD.

Objective assessment of bradykinesia in Parkinson's disease using a serious game

“…The game consists of four phases (Fig. 1), each representing a bee worker's task in the real world (21). The objectives of each phase are as follows:…”

“…The need of technology for objective, collaborative, and unbiased assessment of bradykinesia motivated the development of a serious game so-called RehaBEElitation (https://rehabeelitation-lcoms.univlorraine.fr/ -Brazilian National Institute of Industrial Property (INPI), registration number: BR512021001975-0), which features four phases (21). The interaction with the game is possible through a human-machine interface (HMI) device (wearable glove) designed speci cally for this application, which includes inertial sensors and conductive thread sewn on the device (22,23).…”

“…The usability of the game was evaluated, and the results revealed that RehaBEElitation is a serious game with a simple and intuitive narrative, which is compatible with the players' mental models. This facilitated the interaction of individuals with the serious game and contributed to the great acceptance of the whole system (21,24). This study is an extension of a previous one (25), which evaluated the bradykinesia of individuals with PD only for two phases of the game.…”