<i>Rhodococcus</i>

Jones, Amanda; Goodfellow, Michael

doi:10.1002/9781118960608.gbm00033

Cited by 8 publications

(4 citation statements)

References 301 publications

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“…Rhodococcus sp. are Gram-positive to Gram-variable actinomycetes, are ubiquitous in soil and water, and are most commonly known for causing opportunistic infections of immunocompromised patients, particularly those with HIV [ 300 , 301 ]. The virulence factors of Rhodococcus equi include polysaccharide capsules, hemolytic enzymes, β-lactamases, and the ability to multiply inside macrophages [ 302 ].…”

Section: Hapax Legomenon Isolatesmentioning

confidence: 99%

Ocular Bacterial Infections: A Ten-Year Survey and Review of Causative Organisms Based on the Oklahoma Experience

Astley,

Mursalin,

Coburn

et al. 2023

Microorganisms

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Ocular infections can be medical emergencies that result in permanent visual impairment or blindness and loss of quality of life. Bacteria are a major cause of ocular infections. Effective treatment of ocular infections requires knowledge of which bacteria are the likely cause of the infection. This survey of ocular bacterial isolates and review of ocular pathogens is based on a survey of a collection of isolates banked over a ten-year span at the Dean McGee Eye Institute in Oklahoma. These findings illustrate the diversity of bacteria isolated from the eye, ranging from common species to rare and unique species. At all sampled sites, staphylococci were the predominant bacteria isolated. Pseudomonads were the most common Gram-negative bacterial isolate, except in vitreous, where Serratia was the most common Gram-negative bacterial isolate. Here, we discuss the range of ocular infections that these species have been documented to cause and treatment options for these infections. Although a highly diverse spectrum of species has been isolated from the eye, the majority of infections are caused by Gram-positive species, and in most infections, empiric treatments are effective.

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Section: Hapax Legomenon Isolatesmentioning

confidence: 99%

Ocular Bacterial Infections: A Ten-Year Survey and Review of Causative Organisms Based on the Oklahoma Experience

Astley,

Mursalin,

Coburn

et al. 2023

Microorganisms

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“…However, some genera cannot reproduce through these usual strategies. The Rhodococcus genus reproduces through the formation of rods or cocci, with mycelial formation often referred to as weak or restrictive to development 21 …”

Section: Microbiology Of Actinomycetesmentioning

confidence: 99%

Genus Streptomyces: Recent advances for biotechnological purposes

Júnior

Sousa²,

Oliveira

et al. 2023

Biotech and App Biochem

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Actinomycetes are a distinct group of filamentous bacteria. The Streptomyces genus within this group has been extensively studied over the years, with substantial contributions to society and science. This genus is known for its antimicrobial production, as well as antitumor, biopesticide, and immunomodulatory properties. Therefore, the extraordinary plasticity of the Streptomyces genus has inspired new research techniques. The newest way of exploring Streptomyces has comprised the discovery of new natural metabolites and the application of emerging tools such as CRISPR technology in drug discovery. In this narrative review, we explore relevant published literature concerning the ongoing novelties of the Streptomyces genus.

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“…Rhodococcus spp. produce various carotenoid pigments that cause the fawn, yellow-orange, and red color of colonies ( Jones and Goodfellow, 2015 ). The main function of pigments is to protect cells from reactive oxygen species produced by UV radiation and toxic substances ( Cappelletti et al, 2020 ).…”

Section: Production Of Valuable Natural Productsmentioning

confidence: 99%

Rhodococcus strains as a good biotool for neutralizing pharmaceutical pollutants and obtaining therapeutically valuable products: Through the past into the future

2022

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Active pharmaceutical ingredients present a substantial risk when they reach the environment and drinking water sources. As a new type of dangerous pollutants with high chemical resistance and pronounced biological effects, they accumulate everywhere, often in significant concentrations (μg/L) in ecological environments, food chains, organs of farm animals and humans, and cause an intense response from the aquatic and soil microbiota. Rhodococcus spp. (Actinomycetia class), which occupy a dominant position in polluted ecosystems, stand out among other microorganisms with the greatest variety of degradable pollutants and participate in natural attenuation, are considered as active agents with high transforming and degrading impacts on pharmaceutical compounds. Many representatives of rhodococci are promising as unique sources of specific transforming enzymes, quorum quenching tools, natural products and novel antimicrobials, biosurfactants and nanostructures. The review presents the latest knowledge and current trends regarding the use of Rhodococcus spp. in the processes of pharmaceutical pollutants’ biodegradation, as well as in the fields of biocatalysis and biotechnology for the production of targeted pharmaceutical products. The current literature sources presented in the review can be helpful in future research programs aimed at promoting Rhodococcus spp. as potential biodegraders and biotransformers to control pharmaceutical pollution in the environment.

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Rhodococcus

Cited by 8 publications

References 301 publications

Ocular Bacterial Infections: A Ten-Year Survey and Review of Causative Organisms Based on the Oklahoma Experience

Ocular Bacterial Infections: A Ten-Year Survey and Review of Causative Organisms Based on the Oklahoma Experience

Genus Streptomyces: Recent advances for biotechnological purposes

Rhodococcus strains as a good biotool for neutralizing pharmaceutical pollutants and obtaining therapeutically valuable products: Through the past into the future

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