Rosa Damascena mill for treating adults' anxiety, depression, and stress: A systematic review and dose–response meta‐analysis of randomized controlled trials

Abstract

Recent studies have reported conflicting findings on the antianxiety, antidepressant, and anti-stress properties of Rosa Damascena Mill (RDM). Therefore, the present systematic review and meta-analysis were conducted on the effects of RDM for treating anxiety, depression, and stress amongst adults. The online data sources of Cochrane Central Register of Controlled Trials, PubMed, Scopus, Web of Science, Embase, ProQuest, and Scientific Information Database were searched from inception to June 30, 2021. The randomized controlled trials (RCTs), which examined the effects of RDM (in any form of administration) on adults' anxiety, depression, and stress, were included. A random-effects model was applied to pool the data, and a total of 32 publications were included. The results of the meta-analysis revealed that administration of RDM significantly reduced state anxiety (effect size

Evidence for Rosa damascena efficacy in mental disorders in preclinical animal studies and clinical trials: A systematic review

“…Despite the fact that R. damascena has been evaluated in recent systematic reviews for anti‐anxiety (Rasooli et al, 2021), pain‐relieving (Nasiri, Torkaman, Feizi, & Shamloo, 2020), and sleep‐enhancing properties (Rami et al, 2021), no reviews have ever summarized R. damascena 's mechanisms of action in the treatment of mental disorders based on preclinical animal studies and clinical trial assessments. Saffron (Talaei, Moghadam, Tabassi, & Mohajeri, 2015), valerian ( Valeriana officinalis ), Cinnamon ( Cinnamomum zeylanicum ), Banafsha ( Viola Odorata ), Echium ( Echium amoneum ) (Bakhshaei, 2017) have been reported for the treatment of anxiety disorders and depression in PTM, but none of them were emphasized as much as Rosa damascena .…”

“…Despite the fact that R. damascena has been evaluated in recent systematic reviews for anti-anxiety (Rasooli et al, 2021), pain-relieving (Nasiri, Torkaman, Feizi, & Shamloo, 2020), and sleep-enhancing properties (Rami et al, 2021), no reviews have ever summarized R. damascena's mechanisms of action in the treatment of mental disorders based on preclinical animal studies and clinical trial assessments.…”

Effects of acupressure on sleep quality and anxiety of patients with second- or third-degree burns: a randomized sham-controlled trial

“…The psychometric properties of the Persian version of STAI-S have been confirmed by previous investigations [ 46 ]. Also, it is a commonly used tool by Iranian scholars [ 47 ], and its reliability was reported as acceptable among patients with burns [ 17 , 28 ]. In the present study, the coefficient of Cronbach’s alpha for this tool was 0.91.…”

Flower Power: An Overview on Chemistry and Biological Impact of Selected Essential Oils from Blossoms

“…A search request with "Rosa damascena AND essential oil" on pubmed.ncbi.nlm.nih.gov resulted in 40 results in the last 10 years (accessed on 21.09.2023 22 : 59). Concerning psychiatric issues like anxiety, depression, stress [137], and insomnia [138], metaanalyses are available. Furthermore, pain [139] and sexual dysfunctions [140,141] are research topics.…”

“…Clinical studies on the effect of R. damascena oil inhalation or oral intake on psychiatric disorders make up a large proportion of the studies found in the literature. A meta-analysis concluded that the inhalation or oral intake of R. damascena oil influenced state anxiety, depression, and stress positively [137]. Even in exceptional situations, damask rose oil decreased state anxiety and improved sleep, as a randomized controlled trial on inhalation aromatherapy in operating room personnel reported during the COVID-19 pandemic [142].…”