Salmonella entericaSerotype Choleraesuis Infection of the Knee and Femur in a Nonbacteremic Diabetic Patient

Abstract

Osteoarticular infections caused by Salmonella are rare. The rates of osteomyelitis and septic arthritis due to Salmonella are estimated to be less than 1% and 0.1%-0.2%, respectively (Kato et al., 2012). Salmonella enterica serotype Choleraesuis is a nontyphoidal Salmonella, highly pathogenic in humans, usually causing septicemic disease with little or no intestinal involvement. Serotype Choleraesuis accounts for a small percentage of published studies of Salmonella infections in the United States. It is not commonly reported in joint fluid and bones in contrast to serotype Enteritidis and Typhi, where a considerable number of cases have been published. Chen et al. in Taiwan found that 21% of bacteremic patients with this infection subsequently develop focal infections such as septic arthritis, pneumonia, peritonitis, and cutaneous abscess (Chen et al., 1999, Chiu et al., 2004). In contrast, our patient presented with localized osteoarticular infection with Salmonella enterica serotype Cholerasuis, but without evidence of bacteremia.

Salmonella newportcausing osteomyelitis in a patient with diabetes

“…The incidence of septic arthritis is estimated to be even lower, at <0.1–0.2% 7 8. The most commonly responsible species are: S. enteritidis , S. typhimurium and S. typhi 5 7.…”

“…The incidence of septic arthritis is estimated to be even lower, at <0.1–0.2% 7 8. The most commonly responsible species are: S. enteritidis , S. typhimurium and S. typhi 5 7. Patients will present with pain and swelling of the joint, and as plain radiographs are of limited use, an element of clinical suspicion must be maintained to make the diagnosis.…”

“…If human infection does occur, typically it is a mild, localised disease 6 8. The incidence of S. newport has been increasing, and there have also been reports of multiple drug-resistant cases in Canada 7 8. We may, therefore, see more cases of S. newport causing systemic disease in the future.…”

Skin and Soft Tissue Infection and Osteomyelitis Due to Salmonella enteritidis: A Case Report

“…Literatürde bildirilen Salmonella osteomyeliti olgularında sıklıkla immünosüpresyona neden olan bir hastalık, diyabet veya orak hücreli anemi, talasemi gibi altta yatan hastalıklar bildirilmiştir (6,(9)(10)(11)(12). Sy ve arkadaşları (10), bakteriyemisi olmayan diyabetik bir hastada S. enterica serotip Choleraesuis'e bağlı olarak diz eklemi ve femurda gelişen osteoartiküler infeksiyon bildirmiştir.…”

Genomic Identification of Multidrug-Resistant Salmonella Virchow Monophasic Variant Causing Human Septic Arthritis

“…S. Montevideo was another rare Salmonella serovar, identified to induce septic arthritis of the knee in a 59-year-old woman who presented with a painful and swollen right knee associated with a fever of 38.8 °C [ 8 ]. S. Virchow has also been connected with meningitis and knee septic arthritis [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ].…”