<i>Salmonella enterica</i>Serotype Typhi Bacteremia Complicating Pregnancy in the Third Trimester

Guirguis, George; Patel, Keshav C.; Gittens-Williams, Lisa; Apuzzio, Joseph J.; Martimucci, Kristina; Williams, Shauna F.

doi:10.1155/2017/4018096

Cited by 6 publications

(8 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand awaiting blood or stool culture results takes longer time which poses a significant dilemma [9]. Bacteriological culture remains the gold standard for definitive diagnosis of typhoid fever; lack of its immediate availability during the acute febrile illness may limit its use.…”

Section: Discussionmentioning

confidence: 99%

“…Patients who travel to endemic areas during pregnancy should be aware of the risk of acquiring S. typhi. To minimize this risk while traveling, patients should practice strict food hygiene and avoid uncooked foods [9].…”

Section: Discussionmentioning

confidence: 99%

“…For a pregnant patient with S. typhi once delivered, the neonate should be monitored for signs of S. typhi respiratory distress; sepsis, icterus and pneumonia can indicate neonatal infection and may occur up to 10 days after birth [9]. The recommended antibiotic regimen for S. typhi infection in pregnancy is a third-generation cephalosporin or azithromycin.…”

Section: Discussionmentioning

confidence: 99%

“…Salmonella typhi causes septicemia of digestive origin that can cross the placenta resulting in chorioamniotitis. Vertical transmission of S. typhi occurs via transplacental spread of the organism and neonatal infection canals occur by transmission through the lower birth canal or from exposure to maternal blood [9]. The manifestation of S. typhi may vary; however abdominal pain, fever, nausea, and vomiting are usually present.…”

Section: Introductionmentioning

confidence: 99%

“…The manifestation of S. typhi may vary; however abdominal pain, fever, nausea, and vomiting are usually present. In pregnancy, this combination of symptoms presents a diagnostic challenge, as the differential diagnosis of abdominal pain is long [9]. Typhoid and paratyphoid fever are clinically indistinguishable and bacterial culture remains the gold standard for diagnosis [10,11].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Prevalence of Typhoid Infection among Pregnant Women Attending Specialist Hospital Yola, Adamawa State, Nigeria

Kwala

Asika

2020

JALSI

View full text Add to dashboard Cite

Typhoid fever is one of the major and common health problem worldwide. Typhoid fever caused by Salmonella typhi may be a cause of significant morbidity and mortality in both the mother and fetus in developing countries, where sanitation facilities, personal and food hygiene are inadequate. Thus, the present research was a cross-sectional study of Salmonella infection among pregnant women in Specialist Hospital Yola, Nigeria. The objectives of this study is to determine the prevalence of typhoid infection among pregnant women in Adamawa state in relation to age, educational level, occupation and location, explore factors associated with the infection and to provide information on its prevention and control strategies. Serological analyses (Widal test) and bacteriological analyses (stool culture) were carried out and compared among 313 participants. The results obtained showed that 209 (66.77%) of the participants were seropositive for typhoid fever, whereas 188 (60.06%) were positive based on bacteriological technique. Participants between age groups; 26-35 years old had the highest prevalence of 64.10%.There was no statistically significant difference (P>0.05) between the prevalence of typhoid fever among the various age groups of the pregnant women examined. In relation to Educational level, participants with Non-formal education had the highest prevalence of typhoid infection 75.00%. There was no statistically significant difference (P>0.05) between the prevalence of typhoid fever based on the educational level of the pregnant women examined. Based on occupation of the participants, women who were involved in farming recorded the highest prevalence rate of 88.37%.There was statistically significant difference (P< 0.05) between the prevalence of typhoid fever and the occupation of the pregnant women examined. With respect to the location of the participants, subjects belonging to Semi-urban areas recorded the highest prevalence of 80.98%. There was statistically significant difference (P< 0.05) between the prevalence of typhoid fever and the location of the pregnant women examined. Pregnancy state makes the women more vulnerable to typhoid fever by affecting the physiology of pivotal organs, as such causing complications in pregnant women therefore early and prompt diagnosis of the infection is essential.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Prevalence of Typhoid Infection among Pregnant Women Attending Specialist Hospital Yola, Adamawa State, Nigeria

Kwala

Asika

2020

JALSI

View full text Add to dashboard Cite

show abstract

Network Biology Approaches to Identify Molecular and Systems-Level Differences Between Salmonella Pathovars

Ölbei

Kingsley

Korcsmáros

et al. 2018

Methods in Molecular Biology

View full text Add to dashboard Cite

Epidemiology of Multidrug‐Resistant Salmonella Typhi and Paratyphi Isolated From Stool Culture

Ndima Etouke,

Ful Kuh,

Djoumsie Gomseu

et al. 2024

Journal of Tropical Medicine

View full text Add to dashboard Cite

Enteric fever is a significant health problem in developing countries caused by Salmonella enterica serovars Typhi and Paratyphi. Unfortunately, the burden of the disease remains high not only because of the complications related to the disease but also, especially, because of the spread of the strains of Salmonella resistant to antibiotics. The aim of the present study was to evaluate the antibiotic resistance patterns of Salmonella Typhi and Paratyphi clinical isolates as well as the risk factors associated with infection. This cross‐sectional study was conducted from June 2020 to September 2021. One thousand and seventy‐six patients in the age range (1− ≥ 50 years) were recruited including 423 (39.31%) infected with S. Typhi, 115 (10.68%) infected with S. Paratyphi, and 538 (50%) noninfected after obtaining their informed consent using a face‐to‐face interview and questionnaire. The stool samples were collected in clean and sterile boxes reserved for this purpose and were cultured. Demographic parameters such as sex, age, occupation, water source, level of education, as well as clinical signs and symptoms were obtained. The resistance profile determination was carried out by the disk diffusion method. A multivariate logistic regression analysis was performed to identify factors associated with infection. Results of multivariate logistic regression analysis showed positive and significant associations (OR > 1; p < 0.05) between enteric fever and women among the age groups: 1–10 years, 11–20 years, and 21–30 years. These positive associations were also noted in patients who ate shellfish, salads, fruits, and vegetables; in patients who consumed ice cubes; as well as those who consumed food and drinks offered by ambulant merchants. This indicated that they are more likely to be infected by S. enterica than others. The level of multidrug‐resistant (MDR) S. enterica to first‐line antimicrobial agents ampicillin, chloramphenicol, and co‐trimoxazole was high and selectively distributed according to age groups, marital status, profession, level of education, source of water, and lifestyle. The results highlighted the emergence of MDR S. enterica isolated in the study population, demonstrating resistance to first‐line drugs, fluoroquinolones, and third‐generation cephalosporins. Further studies with large‐scale samples are needed to validate the present results and to monitor MDR S. Typhi and S. Paratyphi serovars in other parts of Cameroon.

show abstract

Salmonella entericaSerotype Typhi Bacteremia Complicating Pregnancy in the Third Trimester

Cited by 6 publications

References 14 publications

Prevalence of Typhoid Infection among Pregnant Women Attending Specialist Hospital Yola, Adamawa State, Nigeria

Prevalence of Typhoid Infection among Pregnant Women Attending Specialist Hospital Yola, Adamawa State, Nigeria

Network Biology Approaches to Identify Molecular and Systems-Level Differences Between Salmonella Pathovars

Epidemiology of Multidrug‐Resistant Salmonella Typhi and Paratyphi Isolated From Stool Culture

Contact Info

Product

Resources

About