Salmonella typhimurium in poultry: a review

Dar, Muneer Ahmad; Ahmad, Syed Mudasir; Bhat, Sajad Ahmad; Ahmed, Raashid; Urwat, Uneeb; Mumtaz, Peerzada Tajamul; Dar, Tanveer Ali; Shah, Riaz Ahmad; Ganai, Nazir Ahmad

doi:10.1017/s0043933917000204

Cited by 57 publications

(34 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ST infects intestinal cells and macrophages in the small and large intestinal mucosa. It can pass through the lamina propria and subsequently migrate to other organs via the bloodstream (Ashayerizadeh, et al, 2017;Dar, et al, 2017). Adaptive immune function, such as T and B cell production, does not develop until approximately 2 weeks after hatching; however, chicks are often infected with ST as early as 3 days after hatching (Barrow, et al, 1987;Beal, et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Lactobacillus reuteri Enhances the Mucosal Barrier Function against Heat-killed Salmonella Typhimurium in the Intestine of Broiler Chicks

et al. 2020

View full text Add to dashboard Cite

Salmonella Typhimurium (ST) infection in chickens inhibits their growth and can lead to food-borne diseases in humans. Probiotics are expected to enhance the function of host intestinal barrier against pathogen infection. The aim of our study was to determine the effect of viable Lactobacillus reuteri (LR) on the response of the mucosal barrier function to antigen stimulation in broiler chicks. Day-old male (n＝8) and female (n＝4) broiler chicks were orally administered either 1×10 8 LR or a water-only control, every day for 7 days. After 7 days, either 1×10 8 heatkilled ST (k-ST), or a buffer-only control, was administered via intra-cardiac injection. The ileum and cecum were collected 3 h post-injection, and paraffin sections were prepared for either mRNA extraction (males), or gut permeability tests (females). Villus and crypt lengths were determined via histological analysis. Real-time PCR was used to calculate expression levels of Toll-like receptors (TLRs), pro-inflammatory cytokines, anti-inflammatory cytokines, avian β-defensins, and tight-junction-associated molecules. Gut permeability was assessed using the inverted intestine method. We found that (1) expression of TLR2-1, TLR21, TGF-β2 and TGF-β3 were reduced following k-ST stimulation, but were unaffected by LR-treatment; (2) oral administration of LR led to increased Claudin1, Claudin5, ZO2, and JAM2 expression following k-ST stimulation; (3) cecal permeability was reduced by co-treatment with LR and k-ST, but not by treatment with LR or k-ST alone. These results suggest that LR, as used in this study, may enhance the intestinal mucosal physical barrier function, but not the expression of other immunerelated factors in newly hatched chicks.

show abstract

Section: Introductionmentioning

confidence: 99%

Lactobacillus reuteri Enhances the Mucosal Barrier Function against Heat-killed Salmonella Typhimurium in the Intestine of Broiler Chicks

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Mashooq Ahmad Dar 1,2 , Peerzada Tajamul Mumtaz 1 , Shakil Ahmad Bhat 1 , Qamar Taban 1 , Shabir Ahmad Khan 1 , Tufail Banday 3…”

Section: Author Detailsmentioning

confidence: 99%

“…meat [3]. Serovars S. Enteritidis, S. Typhimurium, S. Heidelberg and S. Newport are linked to such food-borne diseases, with farm animals being reservoirs for these serotypes [4,5].…”

Section: Introductionmentioning

confidence: 99%

Immunopathogenesis of Salmonellosis

Dar¹,

Mumtaz²,

Bhat³

et al. 2020

New Insight Into Brucella Infection and Foodborne Diseases

View full text Add to dashboard Cite

Salmonella is an intracellular pathogenic, gram-negative, facultative anaerobe and non-spore-forming and usually a motile bacillus that leads to salmonellosis in the host. It is a common food-borne disease that ranges from local gastrointestinal inflammation and diarrhoea to life-threatening typhoid fever and presents usually a serious threat to public health due to its socioeconomic value. Inadequate sanitation and impure water help in the propagation of this disease. Despite advancement in the sanitation standards, Salmonella enters the food chain and affects communities globally. There is an immediate need to develop improved vaccines to minimise Salmonella-related illnesses. Some Salmonella serovars infect a wide range of hosts, while others are known to be host restricted. Many different factors determine the adaptability and host specificity of Salmonella. The host-pathogen interactions play a unique role in Salmonella invasion and progression which needs to be studied in detail. This chapter shall focus on our current understanding of Salmonella invasion, pathogenesis and interactions with the host, host specificity and adaptability.

show abstract

“…Firstly, Salmonella Typhimurium is known for his ability to infect birds, contaminate eggs [21] and be transmitted to humans. It is the main agent of salmonellosis in humans.…”

Section: Experimental Infection Of Three-day-old Chicks With Salmonelmentioning

confidence: 99%

Formulation of Improved Traditional Drugs against virulent species of Salmonella spp in Benin: assessment of the properties from Uvaria chamae, Lantana camara and Phyllantus amarus in Benin, West Africa

Lègba

Dougnon

Gbaguidi

et al. 2019

Preprint

View full text Add to dashboard Cite

Background Uvaria chamae (Annonaceae), Phyllantus amarus (Phyllantaceae) and Lantana camara (Verbenaceae) are empirically alleged to be used as Beninese medicinal plants in the treatment of salmonellosis. This study aimed to produce scientific data on in vitro and in vivo efficacy of Uvaria chamae, Lantana camara and Phyllantus amarus on multiresistant Salmonella spp isolated in Benin.Results After in vitro tests on aqueous and ethanolic extracts of Uvaria chamae, Lantana camara and Phyllantus amarus , only the aqueous extract of Uvaria chamae (leaves) showed the best anti- Salmonella ’s activity. It has been used for the following experiments. The induction of salmonellosis revealed 9.0 10 8 CFU/ml was optimal concentration for triggering and maintaining the symptoms in chicks. This infective concentration has been used for in vivo assessment. 24 hours post inoculation later, the symptoms of salmonellosis (wet cloaca, diarrhea stool and somnolence) were observed in infected groups. After seven days of treatment, the rate of reduction of bacterial load at 100 mg / L, 200 mg / L, 400 mg / L of this extract was 85%, 52.38% and 98% respectively in the chicks groups infected with Salmonella Typhimurium ATCC 14028. About the groups infected with Salmonella spp (virulent strain), the rate of reduction of bacterial load at 100 mg / L, 200 mg / L, 400 mg / L of this extract was 0%, 98.66% and 99.33%. The toxicity tests did not show any significant effect of the Uvaria chamae ’s extract on the biochemical and hematological parameters of the chicks.Conclusion The aqueous extract of Uvaria chamae is active in vitro and in vivo on multiresistant strains of Salmonella spp . This plant is a good candidate for the development of an improved traditional medicine for the management of salmonellosis.

show abstract

Salmonella typhimurium in poultry: a review

Cited by 57 publications

References 58 publications

<i>Lactobacillus reuteri</i> Enhances the Mucosal Barrier Function against Heat-killed <i>Salmonella</i> Typhimurium in the Intestine of Broiler Chicks

<i>Lactobacillus reuteri</i> Enhances the Mucosal Barrier Function against Heat-killed <i>Salmonella</i> Typhimurium in the Intestine of Broiler Chicks

Immunopathogenesis of Salmonellosis

Formulation of Improved Traditional Drugs against virulent species of Salmonella spp in Benin: assessment of the properties from Uvaria chamae, Lantana camara and Phyllantus amarus in Benin, West Africa

Contact Info

Product

Resources

About