Scutellaria baicalensis – a small plant with large pro-health biological activities

Abstract

Scutellaria baicalensis, known also as Huang-Qin is a traditional Chinese plant used in medicine for at least 2000 years. The plant is widely distributed in Japan, Korea, Mongolia and Russia, and is listed in Chinese Pharmacopoeia, European Pharmacopoeia and British Pharmacopoeia. The interest in Huang-Qin results from various biological activities which are primarily related to secondary plants metabolites consisting of flavonoids, phenolic compounds and terpenes. It is known that the compounds are active against numerous diseases and protect the organism against harmful pathogenic agents. Particular attention is paid to baicalein, wogonin and oroxylin A – which are characteristic secondary metabolites of the plant. In this paper, we focused on phytochemical analysis and selected biological activities used in periodontal and cardiovascular problems. The presented studies confirm the ability of Huang-Qin to scavenge free radicals, moreover, that it presents anti-bacterial, anti-inflammatory and enzyme inhibitory activities.

Anti-Hyperalgesic Properties of Menthol and Pulegone

“…Menthol and pulegone are cited within this list. Despite this potent anti-inflammatory action, only recent works explore the potential analgesic actions of terpenes ( Guimarães et al, 2013 ; Yang et al, 2019a , 2019b ; Perri et al, 2020 ; Bai et al, 2021 ; Wojtunik-Kulesza et al, 2021 ). Therefore, in the present study, we hypothesized that pulegone might have potent analgesic action on peripheral painful inflammatory sensitization, and tested its in vitro anti-inflammatory effect and cytotoxicity and its in vivo anti-hyperalgesic effects in the Freund’s Complete Adjuvant (CFA)-induced inflammatory pain model.…”

Medicinal Use and Chemical Composition of Scutellaria baicalensis Species

“…Scutellaria baicalensis, known also as Huang-Qin is a traditional Chinese plant used in medicine for at least 2000 years. The plant is widely distributed in Japan, Korea, Mongolia and Russia, and is listed in Chinese Pharmacopoeia, European Pharmacopoeia and British Pharmacopoeia [3]. Medicinal plants in the Scutellaria genus are used in the treatment of various diseases such as gastrointestinal diseases (dysentery, hemorrhoids, stomach pain, constipation), liver and bile diseases (jaundice, hepatitis), neurological diseases (including epilepsy, spasm, insomnia, hysteria).…”