I Secoverine, a Compound With Specific Antimuscarinic Properties

Rat hippocampal muscarinic autoreceptors are similar to the M2 (cardiac) subtype: comparison with hippocampal M1, atrial M2 and ileal M3 receptors

“…Antagonists suggested to be selective for the M3 ileal muscarinic receptor include 4-DAMP (Barlow & Shepherd, 1985), HHSiD (Mutschler & Lambrecht, 1984) and secoverine (Zwagemakers & Claassen, 1980). Amitriptyline was shown to be 29 times more active in blocking striatal muscarinic receptors negatively linked to adenylate cyclase than cortical muscarinic receptors linked to PI turnover (Nomura et al, 1987).…”

The Influence of Human Rights on International Law

“…55 The law of diplomatic protection is a proven method of addressing human rights violations. 56 This is where the old instrument can help the younger human rights to be more effective.…”

“…55 Doran (2011), p. 735. 56 Article 54 (3) (e) of the Rome Statute authorizes the Prosecutor to receive, exceptionally, information or documents under the seal of confidentiality. This information cannot be used at trial but only to generate additional evidence.…”

“…129 et seq. 56 Panel, EC -Measures Affecting the Approval and Marketing of Biotech Products, WT/DS291-293, para. 7.70 et seq.…”

The effects of atropine and secoverine on gastric secretion and motility in the mouse isolated stomach

“…* = P < 0.001. (Zwagemakers & Claassen, 1980;. Thus it would appear that the relative potency of these drugs can vary with the animal species.…”