<i>Situs Inversus Totalis</i> in Twins: A Brief Review and a Life History / Twin Research: Twin Studies of Trisomy 21; Monozygotic Twin Concordance for Bilateral Coronoid Hyperplasia; Prenatal Hormonal Effects in Mixed-Sex Non-Human Primate Litters; Insurance Mandates and Twinning After In Vitro Fertilization / News Reports: First Report of Identical Twin Puppies; Twins Sisters Turn 100; Remembering an Identical Twin Production Designer; New York City Marathon Quadruplets

Segal, Nancy L.

doi:10.1017/thg.2016.101

Cited by 5 publications

(2 citation statements)

References 15 publications

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“…A very rare condition, which may occur in MZ twins, involves the reversal of the internal organs known as situs inversus partialis or totalis [58]. Several case reports of MZ twins with situs inversus are reported in the literature [2,12,31,50,90]. This may be related to the phenomenon of "mirror twins," when the features appear asymmetrical in co-twins.…”

Section: Congenital Disorders and Infant Mortalitymentioning

confidence: 99%

Twin-Singleton Comparisons Across Multiple Domains of Life

Willemsen

Odintsova

Geus

et al. 2021

Twin and Higher-Order Pregnancies

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Section: Congenital Disorders and Infant Mortalitymentioning

confidence: 99%

Twin-Singleton Comparisons Across Multiple Domains of Life

Willemsen

Odintsova

Geus

et al. 2021

Twin and Higher-Order Pregnancies

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“…Situs inversus is seldom seen in identical twins. 2,14 In a multicenter study analysing 1812 individuals, Baneke et al were unable to calculate meaningful heritability for SIT, due to insufficient numbers. 15 The situation may differ for conjoined twins.…”

Section: Embryology Geneticsmentioning

confidence: 99%

Situs Inversus Totalis: A Clinical Review

Eitler¹,

Bibok²,

Telkes³

2022

IJGM

115

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Situs inversus totalis is a rare congenital abnormality characterized by a mirror-image transposition of both the abdominal and the thoracic organs. While this anomaly is known since the ancient times, practicing doctors do not have much experience with it. Laterality is established early in development, and any failure in that process might lead to a wide variety of disorders which may be partial or complete. Situs solitus describes the normal anatomy, situs inversus is the complete reversal, and situs ambiguous is used for any other abnormality of left-right development. Sidedness is regulated by genes: over 100 genes have been linked to laterality defects. Frequency of situs inversus is 1:10,000 and is more frequent in males: 1.5:1. Advanced imaging modalities can be used to assess fine anatomical details, which play a crucial role in these cases to plan radiologic or surgical interventions. Percutaneous biliary procedures, portal vein embolization are really challenging procedures in SIT patients due to the mirror effect. As most surgeons are right-handed, SIT operations can cause difficulties: handling the instruments with their left hand or the pedals with their left foot can be uncomfortable Organ, especially liver transplantation represents an extraordinary surgical challenge. Solutions to overcome the anatomic differences include the use of segment or reduced size graft with rotation, modified piggy-back technique, side to-side caval anastomosis, and vascular conduit. Because of its rarity and special nature, surgical patients with situs inversus may require more flexibility and creativity from the surgical team.

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Left-sided gastroschisis associated with situs inversus totalis

Nam

Kaneko

Intelizano

et al. 2018

Journal of Pediatric Surgery Case Reports

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Cited by 5 publications

References 15 publications

Twin-Singleton Comparisons Across Multiple Domains of Life

Twin-Singleton Comparisons Across Multiple Domains of Life

Situs Inversus Totalis: A Clinical Review

Left-sided gastroschisis associated with situs inversus totalis

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