Maximally supersymmetric SO(10) and SU (6) unified theories are constructed on the orbifold T 2 /(Z 2 × Z ′ 2 ), with one length scale R 5 taken much larger than the other, R 6 . The effective theory below 1/R 6 is found to be the highly successful SU (5) theory in 5D with natural doublet-triplet splitting, no proton decay from operators of dimension four or five, unified mass relations for heavier generations only, and a precise prediction for gauge coupling unification. A more unified gauge symmetry, and the possibility of Higgs doublets being components of the higher dimensional gauge multiplet, are therefore compatible with a large energy interval where physics is described by SU (5) gauge symmetry in 5D. This leads to the distinctive branching ratios for proton decay from SU (5) gauge boson exchange, p → l + π 0 , l + K 0 ,νπ + ,νK + (l = e, µ), for well-motivated locations for matter. Several phenomenological features of the higher unified gauge symmetry are discussed, including the role of an extra U (1) gauge symmetry, which survives compactification, in the generation of neutrino masses.